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Nonalcoholic fatty liver disease: relationship to insulin sensitivity and oxidative stress. Treatment approaches using vitamin E, magnesium, and betaine.
Altern Med Rev 2002; 7(4):276-91AM

Abstract

Nonalcoholic steatotic hepatitis (NASH), the most prevalent form of progressive liver disease in the United States, is considered to be a manifestation of insulin resistance syndrome. There is increasing evidence that steatosis in NASH is a result of the pathology in fat metabolism occurring in obesity and insulin resistance. For steatosis to progress to necroinflammation and fibrosis, however, the theory of mitochondrial oxidative-stress induced cellular damage is receiving wide acceptance. Treatment approaches that address these etiologies are reviewed: betaine, magnesium, and vitamin E.

Authors+Show Affiliations

lpatrick@frontier.net

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12197781

Citation

Patrick, Lyn. "Nonalcoholic Fatty Liver Disease: Relationship to Insulin Sensitivity and Oxidative Stress. Treatment Approaches Using Vitamin E, Magnesium, and Betaine." Alternative Medicine Review : a Journal of Clinical Therapeutic, vol. 7, no. 4, 2002, pp. 276-91.
Patrick L. Nonalcoholic fatty liver disease: relationship to insulin sensitivity and oxidative stress. Treatment approaches using vitamin E, magnesium, and betaine. Altern Med Rev. 2002;7(4):276-91.
Patrick, L. (2002). Nonalcoholic fatty liver disease: relationship to insulin sensitivity and oxidative stress. Treatment approaches using vitamin E, magnesium, and betaine. Alternative Medicine Review : a Journal of Clinical Therapeutic, 7(4), pp. 276-91.
Patrick L. Nonalcoholic Fatty Liver Disease: Relationship to Insulin Sensitivity and Oxidative Stress. Treatment Approaches Using Vitamin E, Magnesium, and Betaine. Altern Med Rev. 2002;7(4):276-91. PubMed PMID: 12197781.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nonalcoholic fatty liver disease: relationship to insulin sensitivity and oxidative stress. Treatment approaches using vitamin E, magnesium, and betaine. A1 - Patrick,Lyn, PY - 2002/8/29/pubmed PY - 2002/10/19/medline PY - 2002/8/29/entrez SP - 276 EP - 91 JF - Alternative medicine review : a journal of clinical therapeutic JO - Altern Med Rev VL - 7 IS - 4 N2 - Nonalcoholic steatotic hepatitis (NASH), the most prevalent form of progressive liver disease in the United States, is considered to be a manifestation of insulin resistance syndrome. There is increasing evidence that steatosis in NASH is a result of the pathology in fat metabolism occurring in obesity and insulin resistance. For steatosis to progress to necroinflammation and fibrosis, however, the theory of mitochondrial oxidative-stress induced cellular damage is receiving wide acceptance. Treatment approaches that address these etiologies are reviewed: betaine, magnesium, and vitamin E. SN - 1089-5159 UR - https://www.unboundmedicine.com/medline/citation/12197781/full_citation L2 - http://archive.foundationalmedicinereview.com/publications/7/4/276.pdf DB - PRIME DP - Unbound Medicine ER -