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[Ginkgo extract in impaired vision--treatment with special extract EGb 761 of impaired vision due to dry senile macular degeneration].
Wien Med Wochenschr 2002; 152(15-16):423-6WM

Abstract

The therapeutic efficacy of Ginkgo special extract Egb 761 was investigated in a controlled, double-blind trial involving 99 patients with impaired vision due to senile, dry macular degeneration. The primary objective target variable was the change in the corrected visual acuity of the more severely impaired eye at baseline, during a six months treatment period with either 240 mg/die (group I = 50 patients) or 60 mg/die (group II = 49 patients) Egb 761. Marked improvement of the study participants' vision was observed in both treatment groups already after four weeks, with more pronounced improvements in group I (acuity increases by 0.13 in group I vs. 0.10 in group II after 24 weeks). The fraction of patients with improvement of visual acuity > or = 0.2 was nearly twice as large in the group treated with 240 mg/die Egb 761 as in patients receiving the lower dosage (p = 0.08). Subjective health impairments, if present, could be improved during treatment as well. The investigator rated a favorable tolerability for both dosages of Egb 761. In conclusion, the results demonstrate the therapeutic efficacy of Egb 761 in patients with senile, dry macular degeneration, with obvious benefits in every-day life.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

ger

PubMed ID

12244891

Citation

Fies, P, and Angelika Dienel. "[Ginkgo Extract in Impaired Vision--treatment With Special Extract EGb 761 of Impaired Vision Due to Dry Senile Macular Degeneration]." Wiener Medizinische Wochenschrift (1946), vol. 152, no. 15-16, 2002, pp. 423-6.
Fies P, Dienel A. [Ginkgo extract in impaired vision--treatment with special extract EGb 761 of impaired vision due to dry senile macular degeneration]. Wien Med Wochenschr. 2002;152(15-16):423-6.
Fies, P., & Dienel, A. (2002). [Ginkgo extract in impaired vision--treatment with special extract EGb 761 of impaired vision due to dry senile macular degeneration]. Wiener Medizinische Wochenschrift (1946), 152(15-16), pp. 423-6.
Fies P, Dienel A. [Ginkgo Extract in Impaired Vision--treatment With Special Extract EGb 761 of Impaired Vision Due to Dry Senile Macular Degeneration]. Wien Med Wochenschr. 2002;152(15-16):423-6. PubMed PMID: 12244891.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Ginkgo extract in impaired vision--treatment with special extract EGb 761 of impaired vision due to dry senile macular degeneration]. AU - Fies,P, AU - Dienel,Angelika, PY - 2002/9/25/pubmed PY - 2002/11/26/medline PY - 2002/9/25/entrez SP - 423 EP - 6 JF - Wiener medizinische Wochenschrift (1946) JO - Wien Med Wochenschr VL - 152 IS - 15-16 N2 - The therapeutic efficacy of Ginkgo special extract Egb 761 was investigated in a controlled, double-blind trial involving 99 patients with impaired vision due to senile, dry macular degeneration. The primary objective target variable was the change in the corrected visual acuity of the more severely impaired eye at baseline, during a six months treatment period with either 240 mg/die (group I = 50 patients) or 60 mg/die (group II = 49 patients) Egb 761. Marked improvement of the study participants' vision was observed in both treatment groups already after four weeks, with more pronounced improvements in group I (acuity increases by 0.13 in group I vs. 0.10 in group II after 24 weeks). The fraction of patients with improvement of visual acuity > or = 0.2 was nearly twice as large in the group treated with 240 mg/die Egb 761 as in patients receiving the lower dosage (p = 0.08). Subjective health impairments, if present, could be improved during treatment as well. The investigator rated a favorable tolerability for both dosages of Egb 761. In conclusion, the results demonstrate the therapeutic efficacy of Egb 761 in patients with senile, dry macular degeneration, with obvious benefits in every-day life. SN - 0043-5341 UR - https://www.unboundmedicine.com/medline/citation/12244891/full_citation L2 - http://www.diseaseinfosearch.org/result/4401 DB - PRIME DP - Unbound Medicine ER -