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Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study.
J Clin Epidemiol. 2003 Feb; 56(2):171-9.JC

Abstract

The objective of this study was to determine the inter-relationships between a range of lifestyle factors and risk of varicose veins to identify which factors may be implicated in the etiology. An age-stratified random sample of 1566 subjects (699 men and 867 women) aged 18 to 64 years was selected from 12 general practices throughout Edinburgh. A detailed self-administered questionnaire was completed, and a comprehensive physical examination determined the presence and severity of varicose veins. The slightly higher age-adjusted prevalence of varicose veins in men than in women (39.7% versus 32.2%) was not explained by adjustment for an extensive range of lifestyle risk factors (male odds ratio [OR] 2.11, 95% confidence interval [CI] 1.51-2.96). In both sexes, increasing height showed a significant relationship with varicose veins (male OR 1.50, 95% CI 1.18-1.93 and female OR 1.26, 95% CI 1.01-1.58). Among women, body mass index was associated with an increased risk of varicose veins (OR 1.26, 95% CI 1.02-1.54). The current study casts doubt as to whether varicose veins occur predominantly in women. In addition, no consistent relationship with any lifestyle factor was shown. Self-reported evidence suggested a familial susceptibility, thereby warranting future genetic studies.

Authors+Show Affiliations

Lee AJ
Wolfson Unit for Prevention of Peripheral Vascular Diseases, Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, United Kingdom. Amanda.Lee@ed.ac.uk
Evans CJ
No affiliation info available
Allan PL
No affiliation info available
Ruckley CV
No affiliation info available
Fowkes FG
No affiliation info available

MeSH

AdolescentAdultAge DistributionBody HeightBody Mass IndexCross-Sectional StudiesFemaleHumansLife StyleMaleMiddle AgedOdds RatioPhysical ExaminationPrevalenceRisk FactorsScotlandSex DistributionSurveys and QuestionnairesVaricose Veins

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12654412

Citation

Lee, Amanda J., et al. "Lifestyle Factors and the Risk of Varicose Veins: Edinburgh Vein Study." Journal of Clinical Epidemiology, vol. 56, no. 2, 2003, pp. 171-9.
Lee AJ, Evans CJ, Allan PL, et al. Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study. J Clin Epidemiol. 2003;56(2):171-9.
Lee, A. J., Evans, C. J., Allan, P. L., Ruckley, C. V., & Fowkes, F. G. (2003). Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study. Journal of Clinical Epidemiology, 56(2), 171-9.
Lee AJ, et al. Lifestyle Factors and the Risk of Varicose Veins: Edinburgh Vein Study. J Clin Epidemiol. 2003;56(2):171-9. PubMed PMID: 12654412.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study. AU - Lee,Amanda J, AU - Evans,Christine J, AU - Allan,Paul L, AU - Ruckley,C Vaughan, AU - Fowkes,F Gerald R, PY - 2003/3/26/pubmed PY - 2003/5/24/medline PY - 2003/3/26/entrez SP - 171 EP - 9 JF - Journal of clinical epidemiology JO - J Clin Epidemiol VL - 56 IS - 2 N2 - The objective of this study was to determine the inter-relationships between a range of lifestyle factors and risk of varicose veins to identify which factors may be implicated in the etiology. An age-stratified random sample of 1566 subjects (699 men and 867 women) aged 18 to 64 years was selected from 12 general practices throughout Edinburgh. A detailed self-administered questionnaire was completed, and a comprehensive physical examination determined the presence and severity of varicose veins. The slightly higher age-adjusted prevalence of varicose veins in men than in women (39.7% versus 32.2%) was not explained by adjustment for an extensive range of lifestyle risk factors (male odds ratio [OR] 2.11, 95% confidence interval [CI] 1.51-2.96). In both sexes, increasing height showed a significant relationship with varicose veins (male OR 1.50, 95% CI 1.18-1.93 and female OR 1.26, 95% CI 1.01-1.58). Among women, body mass index was associated with an increased risk of varicose veins (OR 1.26, 95% CI 1.02-1.54). The current study casts doubt as to whether varicose veins occur predominantly in women. In addition, no consistent relationship with any lifestyle factor was shown. Self-reported evidence suggested a familial susceptibility, thereby warranting future genetic studies. SN - 0895-4356 UR - https://www.unboundmedicine.com/medline/citation/12654412/full_citation DB - PRIME DP - Unbound Medicine ER -