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Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study.

Abstract

The objective of this study was to determine the inter-relationships between a range of lifestyle factors and risk of varicose veins to identify which factors may be implicated in the etiology. An age-stratified random sample of 1566 subjects (699 men and 867 women) aged 18 to 64 years was selected from 12 general practices throughout Edinburgh. A detailed self-administered questionnaire was completed, and a comprehensive physical examination determined the presence and severity of varicose veins. The slightly higher age-adjusted prevalence of varicose veins in men than in women (39.7% versus 32.2%) was not explained by adjustment for an extensive range of lifestyle risk factors (male odds ratio [OR] 2.11, 95% confidence interval [CI] 1.51-2.96). In both sexes, increasing height showed a significant relationship with varicose veins (male OR 1.50, 95% CI 1.18-1.93 and female OR 1.26, 95% CI 1.01-1.58). Among women, body mass index was associated with an increased risk of varicose veins (OR 1.26, 95% CI 1.02-1.54). The current study casts doubt as to whether varicose veins occur predominantly in women. In addition, no consistent relationship with any lifestyle factor was shown. Self-reported evidence suggested a familial susceptibility, thereby warranting future genetic studies.

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  • Authors+Show Affiliations

    ,

    Wolfson Unit for Prevention of Peripheral Vascular Diseases, Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, United Kingdom. Amanda.Lee@ed.ac.uk

    , , ,

    Source

    Journal of clinical epidemiology 56:2 2003 Feb pg 171-9

    MeSH

    Adolescent
    Adult
    Age Distribution
    Body Height
    Body Mass Index
    Cross-Sectional Studies
    Female
    Humans
    Life Style
    Male
    Middle Aged
    Odds Ratio
    Physical Examination
    Prevalence
    Risk Factors
    Scotland
    Sex Distribution
    Surveys and Questionnaires
    Varicose Veins

    Pub Type(s)

    Journal Article
    Multicenter Study
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    12654412

    Citation

    Lee, Amanda J., et al. "Lifestyle Factors and the Risk of Varicose Veins: Edinburgh Vein Study." Journal of Clinical Epidemiology, vol. 56, no. 2, 2003, pp. 171-9.
    Lee AJ, Evans CJ, Allan PL, et al. Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study. J Clin Epidemiol. 2003;56(2):171-9.
    Lee, A. J., Evans, C. J., Allan, P. L., Ruckley, C. V., & Fowkes, F. G. (2003). Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study. Journal of Clinical Epidemiology, 56(2), pp. 171-9.
    Lee AJ, et al. Lifestyle Factors and the Risk of Varicose Veins: Edinburgh Vein Study. J Clin Epidemiol. 2003;56(2):171-9. PubMed PMID: 12654412.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study. AU - Lee,Amanda J, AU - Evans,Christine J, AU - Allan,Paul L, AU - Ruckley,C Vaughan, AU - Fowkes,F Gerald R, PY - 2003/3/26/pubmed PY - 2003/5/24/medline PY - 2003/3/26/entrez SP - 171 EP - 9 JF - Journal of clinical epidemiology JO - J Clin Epidemiol VL - 56 IS - 2 N2 - The objective of this study was to determine the inter-relationships between a range of lifestyle factors and risk of varicose veins to identify which factors may be implicated in the etiology. An age-stratified random sample of 1566 subjects (699 men and 867 women) aged 18 to 64 years was selected from 12 general practices throughout Edinburgh. A detailed self-administered questionnaire was completed, and a comprehensive physical examination determined the presence and severity of varicose veins. The slightly higher age-adjusted prevalence of varicose veins in men than in women (39.7% versus 32.2%) was not explained by adjustment for an extensive range of lifestyle risk factors (male odds ratio [OR] 2.11, 95% confidence interval [CI] 1.51-2.96). In both sexes, increasing height showed a significant relationship with varicose veins (male OR 1.50, 95% CI 1.18-1.93 and female OR 1.26, 95% CI 1.01-1.58). Among women, body mass index was associated with an increased risk of varicose veins (OR 1.26, 95% CI 1.02-1.54). The current study casts doubt as to whether varicose veins occur predominantly in women. In addition, no consistent relationship with any lifestyle factor was shown. Self-reported evidence suggested a familial susceptibility, thereby warranting future genetic studies. SN - 0895-4356 UR - https://www.unboundmedicine.com/medline/citation/12654412/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0895435602005188 DB - PRIME DP - Unbound Medicine ER -