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Stopping smoking can cause constipation.
Addiction 2003; 98(11):1563-7A

Abstract

SETTING

Constipation is mentioned occasionally as a possible tobacco withdrawal symptom, but no systematic data have been published on this issue.

DESIGN

Smokers' clinic patients provided ratings of their level of constipation on three occasions prior to their quit date, and then weekly after they stopped smoking. The total of 1067 participants maintained at least 1 week of continuous abstinence and provided usable data.

FINDINGS

The three precessation ratings of constipation were stable. After cessation of smoking, the ratings increased significantly (P < 0.01). In 514 patients who maintained continuous abstinence for 4 weeks and provided complete data, constipation peaked at 2 weeks but remained elevated over the whole period. The net proportion of patients affected was 17%, including 9% who were symptom-free at baseline and became very or extremely constipated. In patients on nicotine replacement the increase in constipation, although significant, was less than in patients on bupropion.

CONCLUSIONS

Clinicians treating smokers need to be aware of a possibility that one in six quitters develop constipation, and that for about one in 11 the problem can be severe. Descriptions of tobacco withdrawal syndrome should include constipation.

Authors+Show Affiliations

Barts and The London, Queen Mary's School of Medicine and Dentistry, University of London, UK. p.hajek@qmul.ac.ukNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14616182

Citation

Hajek, Peter, et al. "Stopping Smoking Can Cause Constipation." Addiction (Abingdon, England), vol. 98, no. 11, 2003, pp. 1563-7.
Hajek P, Gillison F, McRobbie H. Stopping smoking can cause constipation. Addiction. 2003;98(11):1563-7.
Hajek, P., Gillison, F., & McRobbie, H. (2003). Stopping smoking can cause constipation. Addiction (Abingdon, England), 98(11), pp. 1563-7.
Hajek P, Gillison F, McRobbie H. Stopping Smoking Can Cause Constipation. Addiction. 2003;98(11):1563-7. PubMed PMID: 14616182.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Stopping smoking can cause constipation. AU - Hajek,Peter, AU - Gillison,Fiona, AU - McRobbie,Hayden, PY - 2003/11/18/pubmed PY - 2004/3/3/medline PY - 2003/11/18/entrez SP - 1563 EP - 7 JF - Addiction (Abingdon, England) JO - Addiction VL - 98 IS - 11 N2 - SETTING: Constipation is mentioned occasionally as a possible tobacco withdrawal symptom, but no systematic data have been published on this issue. DESIGN: Smokers' clinic patients provided ratings of their level of constipation on three occasions prior to their quit date, and then weekly after they stopped smoking. The total of 1067 participants maintained at least 1 week of continuous abstinence and provided usable data. FINDINGS: The three precessation ratings of constipation were stable. After cessation of smoking, the ratings increased significantly (P < 0.01). In 514 patients who maintained continuous abstinence for 4 weeks and provided complete data, constipation peaked at 2 weeks but remained elevated over the whole period. The net proportion of patients affected was 17%, including 9% who were symptom-free at baseline and became very or extremely constipated. In patients on nicotine replacement the increase in constipation, although significant, was less than in patients on bupropion. CONCLUSIONS: Clinicians treating smokers need to be aware of a possibility that one in six quitters develop constipation, and that for about one in 11 the problem can be severe. Descriptions of tobacco withdrawal syndrome should include constipation. SN - 0965-2140 UR - https://www.unboundmedicine.com/medline/citation/14616182/full_citation L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&amp;sid=nlm:pubmed&amp;issn=0965-2140&amp;date=2003&amp;volume=98&amp;issue=11&amp;spage=1563 DB - PRIME DP - Unbound Medicine ER -