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Insulin sensitivity in Chinese ovo-lactovegetarians compared with omnivores.

Abstract

AIM

To compare the insulin sensitivity indices between Chinese vegetarians and omnivores.

METHODS

The study included 36 healthy volunteers (vegetarian, n=19; omnivore, n=17) who had normal fasting plasma glucose levels. Each participant completed an insulin suppression test. We compared steady-state plasma glucose (SSPG), fasting insulin, the homeostasis model assessment for insulin sensitivity (HOMA-IR and HOMA %S) and beta-cell function (HOMA %beta) between the groups. We also tested the correlation of SSPG with years on a vegetarian diet.

RESULTS

The omnivore subjects were younger than the vegetarians (55.7+/-3.7 vs 58.6+/-3.6 year of age, P=0.022). There was no difference between the two groups in sex, blood pressure, renal function tests and lipid profiles. The omnivores had higher serum uric acid levels than vegetarians (5.25+/-0.84 vs 4.54+/-0.75 mg/dl, P=0.011). The results of the indices were different between omnivores and vegetarians (SSPG (mean+/-s.d.) 105.4+/-10.2 vs 80.3+/-11.3 mg/dl, P<0.001; fasting insulin, 4.06+/-0.77 vs 3.02+/-1.19 microU/ml, P=0.004; HOMA-IR, 6.75+/-1.31 vs 4.78+/-2.07, P=0.002; HOMA %S, 159.2+/-31.7 vs 264.3+/-171.7%, P=0.018) except insulin secretion index, HOMA %beta (65.6+/-18.0 vs 58.6+/-14.8%, P=0.208). We found a clear linear relation between years on a vegetarian diet and SSPG (r=-0.541, P=0.017).

CONCLUSIONS

The vegetarians were more insulin sensitive than the omnivore counterparts. The degree of insulin sensitivity appeared to be correlated with years on a vegetarian diet.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Division of Endocrinology and Metabolism, Department of Medicine, Buddhist Dalin Tzu Chi General Hospital and School of Medicine, Chia-Yi, Taiwan.

    , ,

    Source

    MeSH

    Aged
    Asian Continental Ancestry Group
    Blood Glucose
    Blood Pressure
    Body Mass Index
    Buddhism
    Dairy Products
    Diet, Vegetarian
    Female
    Food Preferences
    Glucose Tolerance Test
    Homeostasis
    Humans
    Insulin Resistance
    Male
    Meat Products
    Middle Aged
    Taiwan
    Uric Acid

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    14749752

    Citation

    Kuo, C-S, et al. "Insulin Sensitivity in Chinese Ovo-lactovegetarians Compared With Omnivores." European Journal of Clinical Nutrition, vol. 58, no. 2, 2004, pp. 312-6.
    Kuo CS, Lai NS, Ho LT, et al. Insulin sensitivity in Chinese ovo-lactovegetarians compared with omnivores. Eur J Clin Nutr. 2004;58(2):312-6.
    Kuo, C. S., Lai, N. S., Ho, L. T., & Lin, C. L. (2004). Insulin sensitivity in Chinese ovo-lactovegetarians compared with omnivores. European Journal of Clinical Nutrition, 58(2), pp. 312-6.
    Kuo CS, et al. Insulin Sensitivity in Chinese Ovo-lactovegetarians Compared With Omnivores. Eur J Clin Nutr. 2004;58(2):312-6. PubMed PMID: 14749752.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Insulin sensitivity in Chinese ovo-lactovegetarians compared with omnivores. AU - Kuo,C-S, AU - Lai,N-S, AU - Ho,L-T, AU - Lin,C-L, PY - 2004/1/30/pubmed PY - 2004/4/20/medline PY - 2004/1/30/entrez SP - 312 EP - 6 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 58 IS - 2 N2 - AIM: To compare the insulin sensitivity indices between Chinese vegetarians and omnivores. METHODS: The study included 36 healthy volunteers (vegetarian, n=19; omnivore, n=17) who had normal fasting plasma glucose levels. Each participant completed an insulin suppression test. We compared steady-state plasma glucose (SSPG), fasting insulin, the homeostasis model assessment for insulin sensitivity (HOMA-IR and HOMA %S) and beta-cell function (HOMA %beta) between the groups. We also tested the correlation of SSPG with years on a vegetarian diet. RESULTS: The omnivore subjects were younger than the vegetarians (55.7+/-3.7 vs 58.6+/-3.6 year of age, P=0.022). There was no difference between the two groups in sex, blood pressure, renal function tests and lipid profiles. The omnivores had higher serum uric acid levels than vegetarians (5.25+/-0.84 vs 4.54+/-0.75 mg/dl, P=0.011). The results of the indices were different between omnivores and vegetarians (SSPG (mean+/-s.d.) 105.4+/-10.2 vs 80.3+/-11.3 mg/dl, P<0.001; fasting insulin, 4.06+/-0.77 vs 3.02+/-1.19 microU/ml, P=0.004; HOMA-IR, 6.75+/-1.31 vs 4.78+/-2.07, P=0.002; HOMA %S, 159.2+/-31.7 vs 264.3+/-171.7%, P=0.018) except insulin secretion index, HOMA %beta (65.6+/-18.0 vs 58.6+/-14.8%, P=0.208). We found a clear linear relation between years on a vegetarian diet and SSPG (r=-0.541, P=0.017). CONCLUSIONS: The vegetarians were more insulin sensitive than the omnivore counterparts. The degree of insulin sensitivity appeared to be correlated with years on a vegetarian diet. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/14749752/full_citation L2 - http://dx.doi.org/10.1038/sj.ejcn.1601783 DB - PRIME DP - Unbound Medicine ER -