Tags

Type your tag names separated by a space and hit enter

Energy balance and body-weight stability: impact of gene-environment interactions.

Abstract

Studies of monozygotic twins in the context of overfeeding and energy deficit experiments have shown that gene-environment interactions affect energy balance. From a clinical standpoint, this implies that some individuals are more susceptible to body-weight gain or loss than others because of genetic differences. This opens new perspectives in predictive medicine. In the future, health professionals should be able to count on early diagnosis of individuals at risk for developing long-term metabolic problems and obesity or for not responding adequately to clinical interventions. However, before predictive medicine is in a position to contribute significantly to prevention or treatment of patients, an enormous amount of work has to be done to identify all genetic and environmental factors of relevance, and their network of interactions.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Division of Kinesiology, Institute of Nutraceuticals and Functional Foods, Laval University, Ste-Foy, Québec, Canada G1K 7P4. angelo.tremblay@kin.mso.ulaval.ca

    ,

    Source

    The British journal of nutrition 92 Suppl 1: 2004 Aug pg S63-6

    MeSH

    Body Weight
    Diet
    Energy Metabolism
    Environment
    Female
    Genotype
    Humans
    Male
    Metabolic Diseases
    Obesity

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    15384325

    Citation

    Tremblay, Angelo, et al. "Energy Balance and Body-weight Stability: Impact of Gene-environment Interactions." The British Journal of Nutrition, vol. 92 Suppl 1, 2004, pp. S63-6.
    Tremblay A, Pérusse L, Bouchard C. Energy balance and body-weight stability: impact of gene-environment interactions. Br J Nutr. 2004;92 Suppl 1:S63-6.
    Tremblay, A., Pérusse, L., & Bouchard, C. (2004). Energy balance and body-weight stability: impact of gene-environment interactions. The British Journal of Nutrition, 92 Suppl 1, pp. S63-6.
    Tremblay A, Pérusse L, Bouchard C. Energy Balance and Body-weight Stability: Impact of Gene-environment Interactions. Br J Nutr. 2004;92 Suppl 1:S63-6. PubMed PMID: 15384325.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Energy balance and body-weight stability: impact of gene-environment interactions. AU - Tremblay,Angelo, AU - Pérusse,Louis, AU - Bouchard,Claude, PY - 2004/9/24/pubmed PY - 2004/10/1/medline PY - 2004/9/24/entrez SP - S63 EP - 6 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 92 Suppl 1 N2 - Studies of monozygotic twins in the context of overfeeding and energy deficit experiments have shown that gene-environment interactions affect energy balance. From a clinical standpoint, this implies that some individuals are more susceptible to body-weight gain or loss than others because of genetic differences. This opens new perspectives in predictive medicine. In the future, health professionals should be able to count on early diagnosis of individuals at risk for developing long-term metabolic problems and obesity or for not responding adequately to clinical interventions. However, before predictive medicine is in a position to contribute significantly to prevention or treatment of patients, an enormous amount of work has to be done to identify all genetic and environmental factors of relevance, and their network of interactions. SN - 0007-1145 UR - https://www.unboundmedicine.com/medline/citation/15384325/full_citation L2 - https://www.cambridge.org/core/product/identifier/S0007114504001771/type/journal_article DB - PRIME DP - Unbound Medicine ER -