Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease.Muscle Nerve. 2005 Feb; 31(2):260-5.MN
Abstract
We report a patient with late-onset celiac disease and neurological manifestations including myopathy, polyneuropathy, and ataxia. Laboratory investigations showed anti-gliadin antibodies and severe vitamin E deficiency. Muscle biopsy revealed inflammatory infiltrates and rimmed vacuoles, similar to those found in inclusion-body myositis. A gluten-free diet and vitamin E supplementation reversed both the clinical neurological manifestations and the abnormalities in the muscle biopsy. Anti-gliadin antibodies were no longer present. This case illustrates the spectrum of neurological complications of celiac disease and documents the occurrence of reversible pathology resembling inclusion-body myopathy in the muscle.
Links
MeSH
Pub Type(s)
Case Reports
Journal Article
Language
eng
PubMed ID
15389648
Citation
Kleopa, Kleopas A., et al. "Reversible Inflammatory and Vacuolar Myopathy With Vitamin E Deficiency in Celiac Disease." Muscle & Nerve, vol. 31, no. 2, 2005, pp. 260-5.
Kleopa KA, Kyriacou K, Zamba-Papanicolaou E, et al. Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease. Muscle Nerve. 2005;31(2):260-5.
Kleopa, K. A., Kyriacou, K., Zamba-Papanicolaou, E., & Kyriakides, T. (2005). Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease. Muscle & Nerve, 31(2), 260-5.
Kleopa KA, et al. Reversible Inflammatory and Vacuolar Myopathy With Vitamin E Deficiency in Celiac Disease. Muscle Nerve. 2005;31(2):260-5. PubMed PMID: 15389648.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease.
AU - Kleopa,Kleopas A,
AU - Kyriacou,Kyriacos,
AU - Zamba-Papanicolaou,Eleni,
AU - Kyriakides,Theodoros,
PY - 2004/9/25/pubmed
PY - 2005/3/11/medline
PY - 2004/9/25/entrez
SP - 260
EP - 5
JF - Muscle & nerve
JO - Muscle Nerve
VL - 31
IS - 2
N2 - We report a patient with late-onset celiac disease and neurological manifestations including myopathy, polyneuropathy, and ataxia. Laboratory investigations showed anti-gliadin antibodies and severe vitamin E deficiency. Muscle biopsy revealed inflammatory infiltrates and rimmed vacuoles, similar to those found in inclusion-body myositis. A gluten-free diet and vitamin E supplementation reversed both the clinical neurological manifestations and the abnormalities in the muscle biopsy. Anti-gliadin antibodies were no longer present. This case illustrates the spectrum of neurological complications of celiac disease and documents the occurrence of reversible pathology resembling inclusion-body myopathy in the muscle.
SN - 0148-639X
UR - https://www.unboundmedicine.com/medline/citation/15389648/full_citation
L2 - https://doi.org/10.1002/mus.20144
DB - PRIME
DP - Unbound Medicine
ER -