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Serum levels of antioxidant vitamins, copper, zinc and magnesium in children with chronic rhinosinusitis.

Abstract

Reactive oxygen species including hydroxyl radicals, superoxide anions and hydrogen peroxide which are produced by activated granulocytes play an essential role in many biochemical processes and diseases. Oxidant-mediated tissue damage may be important in the development of chronic sinusitis. The aim of this study was to investigate the serum levels of antioxidant vitamins and elements in 24 children (14 boys and 10 girls, age range: 7-12 years, mean age: 9.2 years) with chronic rhinosinusitis, compared to 20 age and sex matched healthy children. Blood samples were collected in the morning before breakfast and prior to any medication. Vitamin A, E and C levels were determined using reagent kits for high performance liquid chromatography. Cu, Zn and Mg levels were analyzed by atomic absorption spectrometry. Vitamin E, vitamin C, Cu and Zn levels were significantly lower in the patients group than in the control group. However, vitamin A and Mg levels did not differ. In conclusion, serum levels of antioxidant vitamins and elements may be important in the pathogenesis and treatment of chronic rhinosinusitis in children.

Authors+Show Affiliations

,

Mersin University School of Medicine, Department of Otorhinolaryngology, Mersin, Turkey. muunal@hotmail.com

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Source

MeSH

Antioxidants
Ascorbic Acid
Child
Chronic Disease
Copper
Female
Humans
Magnesium
Male
Sinusitis
Vitamin A
Vitamin E
Vitamins
Zinc

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15646267

Citation

Unal, Murat, et al. "Serum Levels of Antioxidant Vitamins, Copper, Zinc and Magnesium in Children With Chronic Rhinosinusitis." Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS), vol. 18, no. 2, 2004, pp. 189-92.
Unal M, Tamer L, Pata YS, et al. Serum levels of antioxidant vitamins, copper, zinc and magnesium in children with chronic rhinosinusitis. J Trace Elem Med Biol. 2004;18(2):189-92.
Unal, M., Tamer, L., Pata, Y. S., Kilic, S., Degirmenci, U., Akbaş, Y., ... Atik, U. (2004). Serum levels of antioxidant vitamins, copper, zinc and magnesium in children with chronic rhinosinusitis. Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS), 18(2), pp. 189-92.
Unal M, et al. Serum Levels of Antioxidant Vitamins, Copper, Zinc and Magnesium in Children With Chronic Rhinosinusitis. J Trace Elem Med Biol. 2004;18(2):189-92. PubMed PMID: 15646267.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum levels of antioxidant vitamins, copper, zinc and magnesium in children with chronic rhinosinusitis. AU - Unal,Murat, AU - Tamer,Lülüfer, AU - Pata,Yavuz Selim, AU - Kilic,Serkan, AU - Degirmenci,Ulaş, AU - Akbaş,Yücel, AU - Görür,Kemal, AU - Atik,Uğur, PY - 2005/1/14/pubmed PY - 2005/4/19/medline PY - 2005/1/14/entrez SP - 189 EP - 92 JF - Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) JO - J Trace Elem Med Biol VL - 18 IS - 2 N2 - Reactive oxygen species including hydroxyl radicals, superoxide anions and hydrogen peroxide which are produced by activated granulocytes play an essential role in many biochemical processes and diseases. Oxidant-mediated tissue damage may be important in the development of chronic sinusitis. The aim of this study was to investigate the serum levels of antioxidant vitamins and elements in 24 children (14 boys and 10 girls, age range: 7-12 years, mean age: 9.2 years) with chronic rhinosinusitis, compared to 20 age and sex matched healthy children. Blood samples were collected in the morning before breakfast and prior to any medication. Vitamin A, E and C levels were determined using reagent kits for high performance liquid chromatography. Cu, Zn and Mg levels were analyzed by atomic absorption spectrometry. Vitamin E, vitamin C, Cu and Zn levels were significantly lower in the patients group than in the control group. However, vitamin A and Mg levels did not differ. In conclusion, serum levels of antioxidant vitamins and elements may be important in the pathogenesis and treatment of chronic rhinosinusitis in children. SN - 0946-672X UR - https://www.unboundmedicine.com/medline/citation/15646267/full_citation L2 - https://medlineplus.gov/sinusitis.html DB - PRIME DP - Unbound Medicine ER -