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Inflammatory bowel disease. Part II: Crohn's disease--pathophysiology and conventional and alternative treatment options.

Abstract

Crohn's disease, a subcategory of inflammatory bowel disease, contributes to significant morbidity, particularly in industrialized nations. It can affect people of any age, but is more commonly diagnosed in adolescence and young adulthood. Inflammation and ulceration occurs primarily in the terminal ileum and colon, although any portion of the intestinal tract can be affected. No etiology has been identified for Crohn's disease, although a number of factors contribute to its etiopathogenesis, including genetic, microbial, inflammatory, immune, and permeability abnormalities. Conventional medications are not curative but can contribute to resolution of acute flare-ups and help maintain remission. Because significant side effects are associated with many these medications, more natural interventions to help maintain remission should be considered. Associated nutrient deficiencies, dietary interventions, and nutrient and botanical supplementation are discussed.

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    MeSH

    Crohn Disease
    Humans
    Intestine, Small
    Permeability
    Risk Factors

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    15656711

    Citation

    Head, Kathleen, and Julie S. Jurenka. "Inflammatory Bowel Disease. Part II: Crohn's Disease--pathophysiology and Conventional and Alternative Treatment Options." Alternative Medicine Review : a Journal of Clinical Therapeutic, vol. 9, no. 4, 2004, pp. 360-401.
    Head K, Jurenka JS. Inflammatory bowel disease. Part II: Crohn's disease--pathophysiology and conventional and alternative treatment options. Altern Med Rev. 2004;9(4):360-401.
    Head, K., & Jurenka, J. S. (2004). Inflammatory bowel disease. Part II: Crohn's disease--pathophysiology and conventional and alternative treatment options. Alternative Medicine Review : a Journal of Clinical Therapeutic, 9(4), pp. 360-401.
    Head K, Jurenka JS. Inflammatory Bowel Disease. Part II: Crohn's Disease--pathophysiology and Conventional and Alternative Treatment Options. Altern Med Rev. 2004;9(4):360-401. PubMed PMID: 15656711.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Inflammatory bowel disease. Part II: Crohn's disease--pathophysiology and conventional and alternative treatment options. AU - Head,Kathleen, AU - Jurenka,Julie S, PY - 2005/1/20/pubmed PY - 2005/2/23/medline PY - 2005/1/20/entrez SP - 360 EP - 401 JF - Alternative medicine review : a journal of clinical therapeutic JO - Altern Med Rev VL - 9 IS - 4 N2 - Crohn's disease, a subcategory of inflammatory bowel disease, contributes to significant morbidity, particularly in industrialized nations. It can affect people of any age, but is more commonly diagnosed in adolescence and young adulthood. Inflammation and ulceration occurs primarily in the terminal ileum and colon, although any portion of the intestinal tract can be affected. No etiology has been identified for Crohn's disease, although a number of factors contribute to its etiopathogenesis, including genetic, microbial, inflammatory, immune, and permeability abnormalities. Conventional medications are not curative but can contribute to resolution of acute flare-ups and help maintain remission. Because significant side effects are associated with many these medications, more natural interventions to help maintain remission should be considered. Associated nutrient deficiencies, dietary interventions, and nutrient and botanical supplementation are discussed. SN - 1089-5159 UR - https://www.unboundmedicine.com/medline/citation/15656711/full_citation L2 - http://archive.foundationalmedicinereview.com/publications/9/4/360.pdf DB - PRIME DP - Unbound Medicine ER -