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Soft drink consumption and urinary stone recurrence: a randomized prevention trial.

Abstract

The object of this study was to determine if a strong association between soft drink (soda) consumption and recurrence of urinary stone disease, found in an earlier case-control study of adult males, had a causal component. The study sample consisted of 1009 male subjects, who completed an episode of urinary stone disease, who were aged 18-75 at that time, and who reported consuming at least 160 ml per day of soft drinks. Half of the subjects were randomized to refrain from consuming soft drinks, while the remaining subjects served as controls. The intervention group had an observed 6.4% advantage in actuarial 3 yr freedom from recurrence (p = 0.023 one-sided) over the control group. One important secondary finding was that for those who reported at the time of the index stone that their most consumed drink was acidified by phosphoric acid but not citric acid, the experimental group had a 15% higher 3 yr recurrence-free rate than the controls, p = 0.002, while for those who reported at the time of the index stone that their most consumed drink was acidified by citric acid with or without phosphoric acid, the experimental group had a similar 3 yr recurrence-free rate to the controls, p = 0.55. This interaction was significant, p = 0.019.

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  • Authors+Show Affiliations

    ,

    Research Assistance Corp, Gainesville, FL 32605.

    , , , , , , , ,

    Source

    Journal of clinical epidemiology 45:8 1992 Aug pg 911-6

    MeSH

    Actuarial Analysis
    Adolescent
    Adult
    Aged
    Beverages
    Citrates
    Citric Acid
    Humans
    Male
    Middle Aged
    Patient Compliance
    Phosphoric Acids
    Recurrence
    Urinary Calculi

    Pub Type(s)

    Clinical Trial
    Journal Article
    Randomized Controlled Trial
    Research Support, Non-U.S. Gov't
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    1624973

    Citation

    Shuster, J, et al. "Soft Drink Consumption and Urinary Stone Recurrence: a Randomized Prevention Trial." Journal of Clinical Epidemiology, vol. 45, no. 8, 1992, pp. 911-6.
    Shuster J, Jenkins A, Logan C, et al. Soft drink consumption and urinary stone recurrence: a randomized prevention trial. J Clin Epidemiol. 1992;45(8):911-6.
    Shuster, J., Jenkins, A., Logan, C., Barnett, T., Riehle, R., Zackson, D., ... Malik, I. (1992). Soft drink consumption and urinary stone recurrence: a randomized prevention trial. Journal of Clinical Epidemiology, 45(8), pp. 911-6.
    Shuster J, et al. Soft Drink Consumption and Urinary Stone Recurrence: a Randomized Prevention Trial. J Clin Epidemiol. 1992;45(8):911-6. PubMed PMID: 1624973.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Soft drink consumption and urinary stone recurrence: a randomized prevention trial. A1 - Shuster,J, AU - Jenkins,A, AU - Logan,C, AU - Barnett,T, AU - Riehle,R, AU - Zackson,D, AU - Wolfe,H, AU - Dale,R, AU - Daley,M, AU - Malik,I, PY - 1992/8/1/pubmed PY - 1992/8/1/medline PY - 1992/8/1/entrez SP - 911 EP - 6 JF - Journal of clinical epidemiology JO - J Clin Epidemiol VL - 45 IS - 8 N2 - The object of this study was to determine if a strong association between soft drink (soda) consumption and recurrence of urinary stone disease, found in an earlier case-control study of adult males, had a causal component. The study sample consisted of 1009 male subjects, who completed an episode of urinary stone disease, who were aged 18-75 at that time, and who reported consuming at least 160 ml per day of soft drinks. Half of the subjects were randomized to refrain from consuming soft drinks, while the remaining subjects served as controls. The intervention group had an observed 6.4% advantage in actuarial 3 yr freedom from recurrence (p = 0.023 one-sided) over the control group. One important secondary finding was that for those who reported at the time of the index stone that their most consumed drink was acidified by phosphoric acid but not citric acid, the experimental group had a 15% higher 3 yr recurrence-free rate than the controls, p = 0.002, while for those who reported at the time of the index stone that their most consumed drink was acidified by citric acid with or without phosphoric acid, the experimental group had a similar 3 yr recurrence-free rate to the controls, p = 0.55. This interaction was significant, p = 0.019. SN - 0895-4356 UR - https://www.unboundmedicine.com/medline/citation/1624973/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/0895-4356(92)90074-W DB - PRIME DP - Unbound Medicine ER -