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Type 2 diabetes in children and adolescents--the next epidemic?
Curr Med Res Opin 2006; 22(2):297-306CM

Abstract

OBJECTIVE

To provide an overview of the incidence of type 2 diabetes in children and adolescents and provide direction for clinicians who care for children and adolescents.

RESEARCH DESIGN AND METHOD

The data presented in this review were obtained from published literature and abstracts presented at scientific meetings. Clinical trials and review articles were identified using the search terms 'metabolic syndrome', 'type 2 diabetes mellitus', 'children', and 'adolescents' in a MEDLINE search from 1995-2005. Additionally, the bibliographies of the identified articles were reviewed.

RESULTS

Type 2 diabetes is rising rapidly in children and adolescents worldwide. Changing a child's living environment to include physical activity, and a well balanced, low fat, high fiber diet, are important for the maintenance of a desirable body weight and improving insulin sensitivity. Maintaining euglycemia with metformin, sulfonylureas, thiazolinediones, and insulin is recommended. Effective treatment of co-morbid problems such as hypertension and dyslipidemia can decrease the risk of cardiovascular complications.

CONCLUSIONS

The prevalence of type 2 diabetes in children will continue to rise until effective measures are taken to prevent obesity in this age group. Ensuring that children have a well-balanced low fat, high fiber, diet, combined with physical activity, will promote weight loss or maintenance, improve insulin sensitivity, and decrease the risk of diabetes and cardiovascular disease. Pharmacologic therapy is recommended for children who are unable to achieve satisfactory glycemic control through physical activity and diet.

Authors+Show Affiliations

Western University of Health Sciences, College of Pharmacy, Pomona, California 91766-1854, USA. evivian@westernu.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16466601

Citation

Vivian, Eva M.. "Type 2 Diabetes in Children and Adolescents--the Next Epidemic?" Current Medical Research and Opinion, vol. 22, no. 2, 2006, pp. 297-306.
Vivian EM. Type 2 diabetes in children and adolescents--the next epidemic? Curr Med Res Opin. 2006;22(2):297-306.
Vivian, E. M. (2006). Type 2 diabetes in children and adolescents--the next epidemic? Current Medical Research and Opinion, 22(2), pp. 297-306.
Vivian EM. Type 2 Diabetes in Children and Adolescents--the Next Epidemic. Curr Med Res Opin. 2006;22(2):297-306. PubMed PMID: 16466601.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Type 2 diabetes in children and adolescents--the next epidemic? A1 - Vivian,Eva M, PY - 2006/2/10/pubmed PY - 2006/4/18/medline PY - 2006/2/10/entrez SP - 297 EP - 306 JF - Current medical research and opinion JO - Curr Med Res Opin VL - 22 IS - 2 N2 - OBJECTIVE: To provide an overview of the incidence of type 2 diabetes in children and adolescents and provide direction for clinicians who care for children and adolescents. RESEARCH DESIGN AND METHOD: The data presented in this review were obtained from published literature and abstracts presented at scientific meetings. Clinical trials and review articles were identified using the search terms 'metabolic syndrome', 'type 2 diabetes mellitus', 'children', and 'adolescents' in a MEDLINE search from 1995-2005. Additionally, the bibliographies of the identified articles were reviewed. RESULTS: Type 2 diabetes is rising rapidly in children and adolescents worldwide. Changing a child's living environment to include physical activity, and a well balanced, low fat, high fiber diet, are important for the maintenance of a desirable body weight and improving insulin sensitivity. Maintaining euglycemia with metformin, sulfonylureas, thiazolinediones, and insulin is recommended. Effective treatment of co-morbid problems such as hypertension and dyslipidemia can decrease the risk of cardiovascular complications. CONCLUSIONS: The prevalence of type 2 diabetes in children will continue to rise until effective measures are taken to prevent obesity in this age group. Ensuring that children have a well-balanced low fat, high fiber, diet, combined with physical activity, will promote weight loss or maintenance, improve insulin sensitivity, and decrease the risk of diabetes and cardiovascular disease. Pharmacologic therapy is recommended for children who are unable to achieve satisfactory glycemic control through physical activity and diet. SN - 0300-7995 UR - https://www.unboundmedicine.com/medline/citation/16466601/full_citation L2 - http://www.tandfonline.com/doi/full/10.1185/030079906X80495 DB - PRIME DP - Unbound Medicine ER -