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Epidemiology and risk factors for pancreatic cancer.

Abstract

Pancreas cancer is considered an 'orphan' cancer because of its relative low incidence. Unfortunately even with early diagnosis, mortality rates are high, explaining why, despite the low incidence, it ranks eighth in a world listing of cancer mortality. International incidence rates vary in different countries, implying that environmental factors are important. Of these factors, smoking is the most well documented etiologic agent, explaining about 25% of all cases. Dietary factors may be important, but it has been difficult to define specific items which either increase or decrease the risk of pancreatic cancer. Since the incidence of pancreas cancer is so strongly age-dependent, we can anticipate an increasing number of patients as the population of most Western countries ages.

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  • Authors+Show Affiliations

    ,

    Department of Surgery, New York Medical College, Munger Pavilion, Valhalla, NY 10595, USA. lowenfel@nymc.edu

    Source

    MeSH

    Anti-Inflammatory Agents, Non-Steroidal
    Bacterial Infections
    Diabetes Complications
    Diet
    Humans
    Hypersensitivity
    Pancreatic Neoplasms
    Pancreatitis, Chronic
    Parasitic Diseases
    Risk Factors
    Smoking
    Virus Diseases

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    16549324

    Citation

    Lowenfels, Albert B., and Patrick Maisonneuve. "Epidemiology and Risk Factors for Pancreatic Cancer." Best Practice & Research. Clinical Gastroenterology, vol. 20, no. 2, 2006, pp. 197-209.
    Lowenfels AB, Maisonneuve P. Epidemiology and risk factors for pancreatic cancer. Best Pract Res Clin Gastroenterol. 2006;20(2):197-209.
    Lowenfels, A. B., & Maisonneuve, P. (2006). Epidemiology and risk factors for pancreatic cancer. Best Practice & Research. Clinical Gastroenterology, 20(2), pp. 197-209.
    Lowenfels AB, Maisonneuve P. Epidemiology and Risk Factors for Pancreatic Cancer. Best Pract Res Clin Gastroenterol. 2006;20(2):197-209. PubMed PMID: 16549324.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Epidemiology and risk factors for pancreatic cancer. AU - Lowenfels,Albert B, AU - Maisonneuve,Patrick, PY - 2006/3/22/pubmed PY - 2006/9/13/medline PY - 2006/3/22/entrez SP - 197 EP - 209 JF - Best practice & research. Clinical gastroenterology JO - Best Pract Res Clin Gastroenterol VL - 20 IS - 2 N2 - Pancreas cancer is considered an 'orphan' cancer because of its relative low incidence. Unfortunately even with early diagnosis, mortality rates are high, explaining why, despite the low incidence, it ranks eighth in a world listing of cancer mortality. International incidence rates vary in different countries, implying that environmental factors are important. Of these factors, smoking is the most well documented etiologic agent, explaining about 25% of all cases. Dietary factors may be important, but it has been difficult to define specific items which either increase or decrease the risk of pancreatic cancer. Since the incidence of pancreas cancer is so strongly age-dependent, we can anticipate an increasing number of patients as the population of most Western countries ages. SN - 1521-6918 UR - https://www.unboundmedicine.com/medline/citation/16549324/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S1521-6918(05)00154-X DB - PRIME DP - Unbound Medicine ER -