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Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis.

Abstract

Fasting is an effective treatment for rheumatoid arthritis, but most patients relapse on reintroduction of food. The effect of fasting followed by one year of a vegetarian diet was assessed in a randomised, single-blind controlled trial. 27 patients were allocated to a four-week stay at a health farm. After an initial 7-10 day subtotal fast, they were put on an individually adjusted gluten-free vegan diet for 3.5 months. The food was then gradually changed to a lactovegetarian diet for the remainder of the study. A control group of 26 patients stayed for four weeks at a convalescent home, but ate an ordinary diet throughout the whole study period. After four weeks at the health farm the diet group showed a significant improvement in number of tender joints, Ritchie's articular index, number of swollen joints, pain score, duration of morning stiffness, grip strength, erythrocyte sedimentation rate, C-reactive protein, white blood cell count, and a health assessment questionnaire score. In the control group, only pain score improved score. In the control group, only pain score improved significantly. The benefits in the diet group were still present after one year, and evaluation of the whole course showed significant advantages for the diet group in all measured indices. This dietary regimen seems to be a useful supplement to conventional medical treatment of rheumatoid arthritis.

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  • Authors+Show Affiliations

    ,

    Department of General Practice, University of Oslo, Norway.

    , , , , , ,

    Source

    Lancet (London, England) 338:8772 1991 Oct 12 pg 899-902

    MeSH

    Adult
    Aged
    Analysis of Variance
    Arthritis, Rheumatoid
    Diet, Vegetarian
    Fasting
    Female
    Humans
    Male
    Middle Aged
    Placebo Effect
    Single-Blind Method

    Pub Type(s)

    Clinical Trial
    Journal Article
    Randomized Controlled Trial
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    1681264

    Citation

    Kjeldsen-Kragh, J, et al. "Controlled Trial of Fasting and One-year Vegetarian Diet in Rheumatoid Arthritis." Lancet (London, England), vol. 338, no. 8772, 1991, pp. 899-902.
    Kjeldsen-Kragh J, Haugen M, Borchgrevink CF, et al. Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis. Lancet. 1991;338(8772):899-902.
    Kjeldsen-Kragh, J., Haugen, M., Borchgrevink, C. F., Laerum, E., Eek, M., Mowinkel, P., ... Førre, O. (1991). Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis. Lancet (London, England), 338(8772), pp. 899-902.
    Kjeldsen-Kragh J, et al. Controlled Trial of Fasting and One-year Vegetarian Diet in Rheumatoid Arthritis. Lancet. 1991 Oct 12;338(8772):899-902. PubMed PMID: 1681264.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis. AU - Kjeldsen-Kragh,J, AU - Haugen,M, AU - Borchgrevink,C F, AU - Laerum,E, AU - Eek,M, AU - Mowinkel,P, AU - Hovi,K, AU - Førre,O, PY - 1991/10/12/pubmed PY - 1991/10/12/medline PY - 1991/10/12/entrez SP - 899 EP - 902 JF - Lancet (London, England) JO - Lancet VL - 338 IS - 8772 N2 - Fasting is an effective treatment for rheumatoid arthritis, but most patients relapse on reintroduction of food. The effect of fasting followed by one year of a vegetarian diet was assessed in a randomised, single-blind controlled trial. 27 patients were allocated to a four-week stay at a health farm. After an initial 7-10 day subtotal fast, they were put on an individually adjusted gluten-free vegan diet for 3.5 months. The food was then gradually changed to a lactovegetarian diet for the remainder of the study. A control group of 26 patients stayed for four weeks at a convalescent home, but ate an ordinary diet throughout the whole study period. After four weeks at the health farm the diet group showed a significant improvement in number of tender joints, Ritchie's articular index, number of swollen joints, pain score, duration of morning stiffness, grip strength, erythrocyte sedimentation rate, C-reactive protein, white blood cell count, and a health assessment questionnaire score. In the control group, only pain score improved score. In the control group, only pain score improved significantly. The benefits in the diet group were still present after one year, and evaluation of the whole course showed significant advantages for the diet group in all measured indices. This dietary regimen seems to be a useful supplement to conventional medical treatment of rheumatoid arthritis. SN - 0140-6736 UR - https://www.unboundmedicine.com/medline/citation/1681264/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/0140-6736(91)91770-U DB - PRIME DP - Unbound Medicine ER -