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Influence of tobacco use on cataract development.
Br J Ophthalmol 2006; 90(11):1374-7BJ

Abstract

AIM

To study the influence of tobacco use on cataract formation in a rural South Indian population.

METHODS

3924 subjects from the Chennai Glaucoma Study conducted in rural south India underwent a comprehensive eye examination, including Lens Opacities Classification System II grading. Information on tobacco use, type of tobacco (smoking and smokeless), duration and quantity of use was collected.

RESULTS

1705 (male:female (M:F) 1106:599) people used tobacco and were significantly older (mean (standard deviation (SD)) age 55.80 (10.64) years) than non-users (52.23 (10.51); p<0.001). 731 (M:F 730:1) people smoked, 900 (M:F 302:598) used smokeless tobacco, and 74 (M:F, 74:0) used tobacco in both forms. The unadjusted and adjusted (age and sex) odds ratio (OR) for a positive history of tobacco use and cataract was 1.72 (95% confidence interval (CI) 1.51 to 1.96) and 1.39 (95% CI 1.15 to 1.68), respectively. The unadjusted OR for smokers and smokeless tobacco users was 1.04 (95% CI 0.88 to 1.23) and 2.74 (95% CI 2.31 to 3.26), respectively. The adjusted OR was 1.19 (95% CI 0.89 to 1.59) and 1.54 (95% CI 1.22 to 1.95), respectively. No significant association was noted between smoking and any particular type of cataract. Smokeless tobacco use was found to be significantly associated with nuclear cataract even after adjusting for age and sex (OR 1.67, p = 0.067, 95% CI 1.16 to 2.39).

CONCLUSION

Tobacco use was significantly associated with cataract. Smoking was not found to be significantly associated with cataract formation; however, smokeless tobacco use was more strongly associated with cataract.

Authors+Show Affiliations

Medical Research Foundation, Sankara Nethralaya, 18 College Road, Chennai, India 600006.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16837540

Citation

Raju, P, et al. "Influence of Tobacco Use On Cataract Development." The British Journal of Ophthalmology, vol. 90, no. 11, 2006, pp. 1374-7.
Raju P, George R, Ve Ramesh S, et al. Influence of tobacco use on cataract development. Br J Ophthalmol. 2006;90(11):1374-7.
Raju, P., George, R., Ve Ramesh, S., Arvind, H., Baskaran, M., & Vijaya, L. (2006). Influence of tobacco use on cataract development. The British Journal of Ophthalmology, 90(11), pp. 1374-7.
Raju P, et al. Influence of Tobacco Use On Cataract Development. Br J Ophthalmol. 2006;90(11):1374-7. PubMed PMID: 16837540.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of tobacco use on cataract development. AU - Raju,P, AU - George,R, AU - Ve Ramesh,S, AU - Arvind,H, AU - Baskaran,M, AU - Vijaya,L, Y1 - 2006/07/12/ PY - 2006/7/14/pubmed PY - 2006/12/12/medline PY - 2006/7/14/entrez SP - 1374 EP - 7 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 90 IS - 11 N2 - AIM: To study the influence of tobacco use on cataract formation in a rural South Indian population. METHODS: 3924 subjects from the Chennai Glaucoma Study conducted in rural south India underwent a comprehensive eye examination, including Lens Opacities Classification System II grading. Information on tobacco use, type of tobacco (smoking and smokeless), duration and quantity of use was collected. RESULTS: 1705 (male:female (M:F) 1106:599) people used tobacco and were significantly older (mean (standard deviation (SD)) age 55.80 (10.64) years) than non-users (52.23 (10.51); p<0.001). 731 (M:F 730:1) people smoked, 900 (M:F 302:598) used smokeless tobacco, and 74 (M:F, 74:0) used tobacco in both forms. The unadjusted and adjusted (age and sex) odds ratio (OR) for a positive history of tobacco use and cataract was 1.72 (95% confidence interval (CI) 1.51 to 1.96) and 1.39 (95% CI 1.15 to 1.68), respectively. The unadjusted OR for smokers and smokeless tobacco users was 1.04 (95% CI 0.88 to 1.23) and 2.74 (95% CI 2.31 to 3.26), respectively. The adjusted OR was 1.19 (95% CI 0.89 to 1.59) and 1.54 (95% CI 1.22 to 1.95), respectively. No significant association was noted between smoking and any particular type of cataract. Smokeless tobacco use was found to be significantly associated with nuclear cataract even after adjusting for age and sex (OR 1.67, p = 0.067, 95% CI 1.16 to 2.39). CONCLUSION: Tobacco use was significantly associated with cataract. Smoking was not found to be significantly associated with cataract formation; however, smokeless tobacco use was more strongly associated with cataract. SN - 0007-1161 UR - https://www.unboundmedicine.com/medline/citation/16837540/full_citation L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&amp;pmid=16837540 DB - PRIME DP - Unbound Medicine ER -