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Influence of tobacco use on cataract development.

Abstract

AIM

To study the influence of tobacco use on cataract formation in a rural South Indian population.

METHODS

3924 subjects from the Chennai Glaucoma Study conducted in rural south India underwent a comprehensive eye examination, including Lens Opacities Classification System II grading. Information on tobacco use, type of tobacco (smoking and smokeless), duration and quantity of use was collected.

RESULTS

1705 (male:female (M:F) 1106:599) people used tobacco and were significantly older (mean (standard deviation (SD)) age 55.80 (10.64) years) than non-users (52.23 (10.51); p<0.001). 731 (M:F 730:1) people smoked, 900 (M:F 302:598) used smokeless tobacco, and 74 (M:F, 74:0) used tobacco in both forms. The unadjusted and adjusted (age and sex) odds ratio (OR) for a positive history of tobacco use and cataract was 1.72 (95% confidence interval (CI) 1.51 to 1.96) and 1.39 (95% CI 1.15 to 1.68), respectively. The unadjusted OR for smokers and smokeless tobacco users was 1.04 (95% CI 0.88 to 1.23) and 2.74 (95% CI 2.31 to 3.26), respectively. The adjusted OR was 1.19 (95% CI 0.89 to 1.59) and 1.54 (95% CI 1.22 to 1.95), respectively. No significant association was noted between smoking and any particular type of cataract. Smokeless tobacco use was found to be significantly associated with nuclear cataract even after adjusting for age and sex (OR 1.67, p = 0.067, 95% CI 1.16 to 2.39).

CONCLUSION

Tobacco use was significantly associated with cataract. Smoking was not found to be significantly associated with cataract formation; however, smokeless tobacco use was more strongly associated with cataract.

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  • Authors+Show Affiliations

    ,

    Medical Research Foundation, Sankara Nethralaya, 18 College Road, Chennai, India 600006.

    , , , ,

    Source

    The British journal of ophthalmology 90:11 2006 Nov pg 1374-7

    MeSH

    Age Distribution
    Cataract
    Developing Countries
    Female
    Humans
    Incidence
    India
    Male
    Middle Aged
    Multivariate Analysis
    Risk Factors
    Rural Population
    Sex Distribution
    Smoking
    Tobacco, Smokeless

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    16837540

    Citation

    Raju, P, et al. "Influence of Tobacco Use On Cataract Development." The British Journal of Ophthalmology, vol. 90, no. 11, 2006, pp. 1374-7.
    Raju P, George R, Ve Ramesh S, et al. Influence of tobacco use on cataract development. Br J Ophthalmol. 2006;90(11):1374-7.
    Raju, P., George, R., Ve Ramesh, S., Arvind, H., Baskaran, M., & Vijaya, L. (2006). Influence of tobacco use on cataract development. The British Journal of Ophthalmology, 90(11), pp. 1374-7.
    Raju P, et al. Influence of Tobacco Use On Cataract Development. Br J Ophthalmol. 2006;90(11):1374-7. PubMed PMID: 16837540.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Influence of tobacco use on cataract development. AU - Raju,P, AU - George,R, AU - Ve Ramesh,S, AU - Arvind,H, AU - Baskaran,M, AU - Vijaya,L, Y1 - 2006/07/12/ PY - 2006/7/14/pubmed PY - 2006/12/12/medline PY - 2006/7/14/entrez SP - 1374 EP - 7 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 90 IS - 11 N2 - AIM: To study the influence of tobacco use on cataract formation in a rural South Indian population. METHODS: 3924 subjects from the Chennai Glaucoma Study conducted in rural south India underwent a comprehensive eye examination, including Lens Opacities Classification System II grading. Information on tobacco use, type of tobacco (smoking and smokeless), duration and quantity of use was collected. RESULTS: 1705 (male:female (M:F) 1106:599) people used tobacco and were significantly older (mean (standard deviation (SD)) age 55.80 (10.64) years) than non-users (52.23 (10.51); p<0.001). 731 (M:F 730:1) people smoked, 900 (M:F 302:598) used smokeless tobacco, and 74 (M:F, 74:0) used tobacco in both forms. The unadjusted and adjusted (age and sex) odds ratio (OR) for a positive history of tobacco use and cataract was 1.72 (95% confidence interval (CI) 1.51 to 1.96) and 1.39 (95% CI 1.15 to 1.68), respectively. The unadjusted OR for smokers and smokeless tobacco users was 1.04 (95% CI 0.88 to 1.23) and 2.74 (95% CI 2.31 to 3.26), respectively. The adjusted OR was 1.19 (95% CI 0.89 to 1.59) and 1.54 (95% CI 1.22 to 1.95), respectively. No significant association was noted between smoking and any particular type of cataract. Smokeless tobacco use was found to be significantly associated with nuclear cataract even after adjusting for age and sex (OR 1.67, p = 0.067, 95% CI 1.16 to 2.39). CONCLUSION: Tobacco use was significantly associated with cataract. Smoking was not found to be significantly associated with cataract formation; however, smokeless tobacco use was more strongly associated with cataract. SN - 0007-1161 UR - https://www.unboundmedicine.com/medline/citation/16837540/full_citation L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&amp;pmid=16837540 DB - PRIME DP - Unbound Medicine ER -