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The incidence and case-fatality rates of acute biliary, alcoholic, and idiopathic pancreatitis in California, 1994-2001.
Pancreas 2006; 33(4):336-44P

Abstract

OBJECTIVE

To better define the epidemiology of acute pancreatitis in a racially diverse population.

METHODS

Analysis of all patients hospitalized in California with first-time acute pancreatitis for the period between January 1994 and September 2001. Subtypes were classified based on the presence or absence of predisposing conditions.

RESULTS

There were 70,231 patients hospitalized for first-time acute pancreatitis; 32.6% had biliary tract disease alone, 20.3% had alcohol abuse alone, and 36.6% were idiopathic. The age-standardized incidence increased by 32% from 33.2 to 43.8 cases per 100,000 adults for the period between 1994 and 2001, with the largest increase in the biliary group (52%). The standardized incidence rate of alcoholic and idiopathic pancreatitis was highest in African Americans, whereas biliary pancreatitis was highest in Hispanics. There was no change over time in the percentage of patients dying in the first 14 or 91 days; and in a risk-adjusted model, patients with alcoholic pancreatitis had the highest risk of dying.

CONCLUSIONS

The incidence rate of acute pancreatitis rose for the period between 1994 and 2001. However, there was no reduction in the 14- or 91-day case-fatality rate. Further research is needed to explain both the rise in the incidence rate of pancreatitis and the absence of any improvement in the early case-fatality rate.

Authors+Show Affiliations

Department of Surgery, UC Davis Medical Center, Sacramento, CA, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17079936

Citation

Frey, Charles F., et al. "The Incidence and Case-fatality Rates of Acute Biliary, Alcoholic, and Idiopathic Pancreatitis in California, 1994-2001." Pancreas, vol. 33, no. 4, 2006, pp. 336-44.
Frey CF, Zhou H, Harvey DJ, et al. The incidence and case-fatality rates of acute biliary, alcoholic, and idiopathic pancreatitis in California, 1994-2001. Pancreas. 2006;33(4):336-44.
Frey, C. F., Zhou, H., Harvey, D. J., & White, R. H. (2006). The incidence and case-fatality rates of acute biliary, alcoholic, and idiopathic pancreatitis in California, 1994-2001. Pancreas, 33(4), pp. 336-44.
Frey CF, et al. The Incidence and Case-fatality Rates of Acute Biliary, Alcoholic, and Idiopathic Pancreatitis in California, 1994-2001. Pancreas. 2006;33(4):336-44. PubMed PMID: 17079936.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The incidence and case-fatality rates of acute biliary, alcoholic, and idiopathic pancreatitis in California, 1994-2001. AU - Frey,Charles F, AU - Zhou,Hong, AU - Harvey,Danielle J, AU - White,Richard H, PY - 2006/11/3/pubmed PY - 2006/12/9/medline PY - 2006/11/3/entrez SP - 336 EP - 44 JF - Pancreas JO - Pancreas VL - 33 IS - 4 N2 - OBJECTIVE: To better define the epidemiology of acute pancreatitis in a racially diverse population. METHODS: Analysis of all patients hospitalized in California with first-time acute pancreatitis for the period between January 1994 and September 2001. Subtypes were classified based on the presence or absence of predisposing conditions. RESULTS: There were 70,231 patients hospitalized for first-time acute pancreatitis; 32.6% had biliary tract disease alone, 20.3% had alcohol abuse alone, and 36.6% were idiopathic. The age-standardized incidence increased by 32% from 33.2 to 43.8 cases per 100,000 adults for the period between 1994 and 2001, with the largest increase in the biliary group (52%). The standardized incidence rate of alcoholic and idiopathic pancreatitis was highest in African Americans, whereas biliary pancreatitis was highest in Hispanics. There was no change over time in the percentage of patients dying in the first 14 or 91 days; and in a risk-adjusted model, patients with alcoholic pancreatitis had the highest risk of dying. CONCLUSIONS: The incidence rate of acute pancreatitis rose for the period between 1994 and 2001. However, there was no reduction in the 14- or 91-day case-fatality rate. Further research is needed to explain both the rise in the incidence rate of pancreatitis and the absence of any improvement in the early case-fatality rate. SN - 1536-4828 UR - https://www.unboundmedicine.com/medline/citation/17079936/full_citation L2 - http://Insights.ovid.com/pubmed?pmid=17079936 DB - PRIME DP - Unbound Medicine ER -