Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study.
Energy-adjusted magnesium intake was nonsignificantly inversely related to risk of colorectal cancer (n=2328) in the Netherlands Cohort Study on Diet and Cancer that started in 1986 (n=58 279 men and 62 573 women). Statistically significant inverse trends in risk were observed in overweight subjects for colon and proximal colon cancer across increasing quintiles of magnesium uptake (P-trend, 0.05 and 0.02, respectively). Although an overall protective effect was not afforded, our results suggest an effect of magnesium in overweight subjects, possibly through decreasing insulin resistance.
Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. PA.vandenBrandt@epid.unimass.nl, ,
Body Mass Index
Pub Type(s)Journal Article