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Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study.

Abstract

Energy-adjusted magnesium intake was nonsignificantly inversely related to risk of colorectal cancer (n=2328) in the Netherlands Cohort Study on Diet and Cancer that started in 1986 (n=58 279 men and 62 573 women). Statistically significant inverse trends in risk were observed in overweight subjects for colon and proximal colon cancer across increasing quintiles of magnesium uptake (P-trend, 0.05 and 0.02, respectively). Although an overall protective effect was not afforded, our results suggest an effect of magnesium in overweight subjects, possibly through decreasing insulin resistance.

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  • Authors+Show Affiliations

    ,

    Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. PA.vandenBrandt@epid.unimass.nl

    , ,

    Source

    British journal of cancer 96:3 2007 Feb 12 pg 510-3

    MeSH

    Aged
    Body Mass Index
    Cohort Studies
    Colorectal Neoplasms
    Female
    Humans
    Insulin Resistance
    Magnesium
    Male
    Middle Aged
    Netherlands

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    17285123

    Citation

    van den Brandt, P A., et al. "Magnesium Intake and Colorectal Cancer Risk in the Netherlands Cohort Study." British Journal of Cancer, vol. 96, no. 3, 2007, pp. 510-3.
    van den Brandt PA, Smits KM, Goldbohm RA, et al. Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study. Br J Cancer. 2007;96(3):510-3.
    van den Brandt, P. A., Smits, K. M., Goldbohm, R. A., & Weijenberg, M. P. (2007). Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study. British Journal of Cancer, 96(3), pp. 510-3.
    van den Brandt PA, et al. Magnesium Intake and Colorectal Cancer Risk in the Netherlands Cohort Study. Br J Cancer. 2007 Feb 12;96(3):510-3. PubMed PMID: 17285123.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study. AU - van den Brandt,P A, AU - Smits,K M, AU - Goldbohm,R A, AU - Weijenberg,M P, PY - 2007/2/8/pubmed PY - 2007/3/22/medline PY - 2007/2/8/entrez SP - 510 EP - 3 JF - British journal of cancer JO - Br. J. Cancer VL - 96 IS - 3 N2 - Energy-adjusted magnesium intake was nonsignificantly inversely related to risk of colorectal cancer (n=2328) in the Netherlands Cohort Study on Diet and Cancer that started in 1986 (n=58 279 men and 62 573 women). Statistically significant inverse trends in risk were observed in overweight subjects for colon and proximal colon cancer across increasing quintiles of magnesium uptake (P-trend, 0.05 and 0.02, respectively). Although an overall protective effect was not afforded, our results suggest an effect of magnesium in overweight subjects, possibly through decreasing insulin resistance. SN - 0007-0920 UR - https://www.unboundmedicine.com/medline/citation/17285123/full_citation L2 - http://dx.doi.org/10.1038/sj.bjc.6603577 DB - PRIME DP - Unbound Medicine ER -