Tags

Type your tag names separated by a space and hit enter

Carbohydrate nutrition, glycemic index, and the 10-y incidence of cataract.
Am J Clin Nutr 2007; 86(5):1502-8AJ

Abstract

BACKGROUND

Although dietary carbohydrates are thought to play a role in cataractogenesis, few epidemiologic studies have examined links between carbohydrate nutrition and cataract.

OBJECTIVES

We investigated the associations between dietary glycemic index (GI), glycemic load (GL), total carbohydrate intake, and 10-y incident nuclear, cortical, and posterior subcapsular cataract.

DESIGN

Of 3654 baseline participants in an Australian population aged >/=49 y (1992-1994), 933 were seen after 5 and/or 10 y, had completed a detailed semiquantitative food-frequency questionnaire, had no previous cataract surgery or baseline cataract, and had photographs taken to assess incident cataract with the Wisconsin Cataract Grading System. Dietary information was collected with a validated food questionnaire. GI was calculated from a customized database of Australian foods. GI, GL, and all other nutrients were energy adjusted. Hazard ratios (HRs) and 95% CIs were calculated with the use of discrete logistic models.

RESULTS

After age, sex, diabetes, and other factors were controlled for, each SD increase in GI significantly predicted incident cortical cataract (HR: 1.19; 95% CI: 1.01, 1.39). Participants within the highest compared with the lowest quartile of GI were more likely to develop incident cortical cataract (HR: 1.77; 95% CI: 1.13, 2.78; P for trend = 0.035). These findings were similar after excluding participants with diabetes, although they were slightly attenuated and marginally nonsignificant (HR: 1.16; 95% CI: 0.98, 1.37, per SD increase in GI). No association was found between GI and nuclear or posterior subcapsular cataract and between GL or carbohydrate quantity and any cataract subtype.

CONCLUSION

In an Australian cohort, poorer dietary carbohydrate quality, reflected by high GI, predicted incident cortical cataract.

Authors+Show Affiliations

Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Westmead Hospital, Sydney, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17991665

Citation

Tan, Jennifer, et al. "Carbohydrate Nutrition, Glycemic Index, and the 10-y Incidence of Cataract." The American Journal of Clinical Nutrition, vol. 86, no. 5, 2007, pp. 1502-8.
Tan J, Wang JJ, Flood V, et al. Carbohydrate nutrition, glycemic index, and the 10-y incidence of cataract. Am J Clin Nutr. 2007;86(5):1502-8.
Tan, J., Wang, J. J., Flood, V., Kaushik, S., Barclay, A., Brand-Miller, J., & Mitchell, P. (2007). Carbohydrate nutrition, glycemic index, and the 10-y incidence of cataract. The American Journal of Clinical Nutrition, 86(5), pp. 1502-8.
Tan J, et al. Carbohydrate Nutrition, Glycemic Index, and the 10-y Incidence of Cataract. Am J Clin Nutr. 2007;86(5):1502-8. PubMed PMID: 17991665.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carbohydrate nutrition, glycemic index, and the 10-y incidence of cataract. AU - Tan,Jennifer, AU - Wang,Jie Jin, AU - Flood,Victoria, AU - Kaushik,Shweta, AU - Barclay,Alan, AU - Brand-Miller,Jennie, AU - Mitchell,Paul, PY - 2007/11/10/pubmed PY - 2007/12/21/medline PY - 2007/11/10/entrez SP - 1502 EP - 8 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 86 IS - 5 N2 - BACKGROUND: Although dietary carbohydrates are thought to play a role in cataractogenesis, few epidemiologic studies have examined links between carbohydrate nutrition and cataract. OBJECTIVES: We investigated the associations between dietary glycemic index (GI), glycemic load (GL), total carbohydrate intake, and 10-y incident nuclear, cortical, and posterior subcapsular cataract. DESIGN: Of 3654 baseline participants in an Australian population aged >/=49 y (1992-1994), 933 were seen after 5 and/or 10 y, had completed a detailed semiquantitative food-frequency questionnaire, had no previous cataract surgery or baseline cataract, and had photographs taken to assess incident cataract with the Wisconsin Cataract Grading System. Dietary information was collected with a validated food questionnaire. GI was calculated from a customized database of Australian foods. GI, GL, and all other nutrients were energy adjusted. Hazard ratios (HRs) and 95% CIs were calculated with the use of discrete logistic models. RESULTS: After age, sex, diabetes, and other factors were controlled for, each SD increase in GI significantly predicted incident cortical cataract (HR: 1.19; 95% CI: 1.01, 1.39). Participants within the highest compared with the lowest quartile of GI were more likely to develop incident cortical cataract (HR: 1.77; 95% CI: 1.13, 2.78; P for trend = 0.035). These findings were similar after excluding participants with diabetes, although they were slightly attenuated and marginally nonsignificant (HR: 1.16; 95% CI: 0.98, 1.37, per SD increase in GI). No association was found between GI and nuclear or posterior subcapsular cataract and between GL or carbohydrate quantity and any cataract subtype. CONCLUSION: In an Australian cohort, poorer dietary carbohydrate quality, reflected by high GI, predicted incident cortical cataract. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/17991665/full_citation L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/86.5.1502 DB - PRIME DP - Unbound Medicine ER -