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Physical activity decreases diverticular complications.
Am J Gastroenterol 2009; 104(5):1221-30AJ

Abstract

OBJECTIVES

Little is known about the effect of physical activity on diverticular complications. This study prospectively examined the associations between physical activity and diverticular bleeding and diverticulitis.

METHODS

We studied 47,228 US males in the Health Professionals Follow-up Study cohort who were aged 40-75 years and free of diverticular disease, gastrointestinal cancer, and inflammatory bowel disease at baseline in 1986. Men reporting newly diagnosed diverticular disease on biennial follow-up questionnaires were sent supplemental questionnaires outlining details of diagnosis and treatment. Physical activity was assessed every 2 years. Men recorded the average time per week spent in eight recreational activities, and flights of stairs climbed per day. Cox proportional hazards regression was used to calculate relative risks (RRs).

RESULTS

During 18 years of follow-up, 800 cases of diverticulitis and 383 cases of diverticular bleeding were identified. Total cumulative physical activity was associated with a decreased risk of diverticulitis and diverticular bleeding. After adjustment for potential confounders, the RR for men in the highest quintile of total activity (> or = 57.4 metabolic equivalent hours per week (MET-h/week) was 0.75 (95% confidence interval, CI, 0.58-0.95) for diverticulitis and 0.54 (95% CI, 0.38-0.77) for bleeding, as compared with men in the lowest quintile (< or = 8.2 MET-h/week). Vigorous activity was inversely related to diverticulitis in a high vs. low comparison (multivariable RR, 0.66; 95% CI, 0.51-0.86) and bleeding (multivariable RR, 0.61; 95% CI, 0.41-0.90), whereas nonvigorous activity was not. These results were similar for recent (simple updated) and baseline activity.

CONCLUSIONS

Data from this large prospective cohort suggest that physical activity lowers the risk of diverticulitis and diverticular bleeding. Vigorous activity appears to account for this association.

Authors+Show Affiliations

Division of Gastroenterology, Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98104, USA. lisas@medicine.washington.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

19367267

Citation

Strate, Lisa L., et al. "Physical Activity Decreases Diverticular Complications." The American Journal of Gastroenterology, vol. 104, no. 5, 2009, pp. 1221-30.
Strate LL, Liu YL, Aldoori WH, et al. Physical activity decreases diverticular complications. Am J Gastroenterol. 2009;104(5):1221-30.
Strate, L. L., Liu, Y. L., Aldoori, W. H., & Giovannucci, E. L. (2009). Physical activity decreases diverticular complications. The American Journal of Gastroenterology, 104(5), pp. 1221-30. doi:10.1038/ajg.2009.121.
Strate LL, et al. Physical Activity Decreases Diverticular Complications. Am J Gastroenterol. 2009;104(5):1221-30. PubMed PMID: 19367267.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Physical activity decreases diverticular complications. AU - Strate,Lisa L, AU - Liu,Yan L, AU - Aldoori,Walid H, AU - Giovannucci,Edward L, Y1 - 2009/04/14/ PY - 2009/4/16/entrez PY - 2009/4/16/pubmed PY - 2009/6/16/medline SP - 1221 EP - 30 JF - The American journal of gastroenterology JO - Am. J. Gastroenterol. VL - 104 IS - 5 N2 - OBJECTIVES: Little is known about the effect of physical activity on diverticular complications. This study prospectively examined the associations between physical activity and diverticular bleeding and diverticulitis. METHODS: We studied 47,228 US males in the Health Professionals Follow-up Study cohort who were aged 40-75 years and free of diverticular disease, gastrointestinal cancer, and inflammatory bowel disease at baseline in 1986. Men reporting newly diagnosed diverticular disease on biennial follow-up questionnaires were sent supplemental questionnaires outlining details of diagnosis and treatment. Physical activity was assessed every 2 years. Men recorded the average time per week spent in eight recreational activities, and flights of stairs climbed per day. Cox proportional hazards regression was used to calculate relative risks (RRs). RESULTS: During 18 years of follow-up, 800 cases of diverticulitis and 383 cases of diverticular bleeding were identified. Total cumulative physical activity was associated with a decreased risk of diverticulitis and diverticular bleeding. After adjustment for potential confounders, the RR for men in the highest quintile of total activity (> or = 57.4 metabolic equivalent hours per week (MET-h/week) was 0.75 (95% confidence interval, CI, 0.58-0.95) for diverticulitis and 0.54 (95% CI, 0.38-0.77) for bleeding, as compared with men in the lowest quintile (< or = 8.2 MET-h/week). Vigorous activity was inversely related to diverticulitis in a high vs. low comparison (multivariable RR, 0.66; 95% CI, 0.51-0.86) and bleeding (multivariable RR, 0.61; 95% CI, 0.41-0.90), whereas nonvigorous activity was not. These results were similar for recent (simple updated) and baseline activity. CONCLUSIONS: Data from this large prospective cohort suggest that physical activity lowers the risk of diverticulitis and diverticular bleeding. Vigorous activity appears to account for this association. SN - 1572-0241 UR - https://www.unboundmedicine.com/medline/citation/19367267/full_citation L2 - http://Insights.ovid.com/pubmed?pmid=19367267 DB - PRIME DP - Unbound Medicine ER -