Tags

Type your tag names separated by a space and hit enter

Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat.
Maturitas. 2008 Sep-Oct; 61(1-2):27-33.M

Abstract

Plants contain compounds with oestrogen--like action called phytoestrogens. Soy contains daidzin, a potent phytoestrogen, and wheat flour contains less potent enterolactones. We aimed to show in 58 postmenopausal women (age 54, range 30-70 years) with at least 14 hot flushes per week, that their daily diet supplemented with soy flour (n = 28) could reduce flushes compared with wheat flour (n = 30) over 12 weeks when randomised and double blind. Hot flushes significantly decreased in the soy and wheat flour groups (40% and 25% reduction, respectively < 0.001 for both) with a significant rapid response in the soy flour group in 6 weeks (P < 0.001) that continued. Menopausal symptom score decreased significantly in both groups (P < 0.05). Urinary daidzein excretion confirmed compliance. Vaginal cell maturation, plasma lipids and urinary calcium remained unchanged. Serum FSH decreased and urinary hydroxyproline increased in the wheat flour group.

Authors+Show Affiliations

Brighton Medical Clinic, 26 Carpenter St., Brighton 3186, Vic, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19434877

Citation

Murkies, A L., et al. "Dietary Flour Supplementation Decreases Post-menopausal Hot Flushes: Effect of Soy and Wheat." Maturitas, vol. 61, no. 1-2, 2008, pp. 27-33.
Murkies AL, Lombard C, Strauss BJ, et al. Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat. Maturitas. 2008;61(1-2):27-33.
Murkies, A. L., Lombard, C., Strauss, B. J., Wilcox, G., Burger, H. G., & Morton, M. S. (2008). Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat. Maturitas, 61(1-2), 27-33.
Murkies AL, et al. Dietary Flour Supplementation Decreases Post-menopausal Hot Flushes: Effect of Soy and Wheat. Maturitas. 2008 Sep-Oct;61(1-2):27-33. PubMed PMID: 19434877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat. AU - Murkies,A L, AU - Lombard,C, AU - Strauss,B J G, AU - Wilcox,G, AU - Burger,H G, AU - Morton,M S, PY - 2009/5/13/entrez PY - 2009/5/13/pubmed PY - 2009/5/13/medline SP - 27 EP - 33 JF - Maturitas JO - Maturitas VL - 61 IS - 1-2 N2 - Plants contain compounds with oestrogen--like action called phytoestrogens. Soy contains daidzin, a potent phytoestrogen, and wheat flour contains less potent enterolactones. We aimed to show in 58 postmenopausal women (age 54, range 30-70 years) with at least 14 hot flushes per week, that their daily diet supplemented with soy flour (n = 28) could reduce flushes compared with wheat flour (n = 30) over 12 weeks when randomised and double blind. Hot flushes significantly decreased in the soy and wheat flour groups (40% and 25% reduction, respectively < 0.001 for both) with a significant rapid response in the soy flour group in 6 weeks (P < 0.001) that continued. Menopausal symptom score decreased significantly in both groups (P < 0.05). Urinary daidzein excretion confirmed compliance. Vaginal cell maturation, plasma lipids and urinary calcium remained unchanged. Serum FSH decreased and urinary hydroxyproline increased in the wheat flour group. SN - 0378-5122 UR - https://www.unboundmedicine.com/medline/citation/19434877/full_citation L2 - https://ClinicalTrials.gov/search/term=19434877 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.