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Conditions and drugs interfering with thyroxine absorption.

Abstract

Food, dietary fibre and espresso coffee interfere with the absorption of levothyroxine. Malabsorptive disorders reported to affect the absorption of levothyroxine include coeliac disease, inflammatory bowel disease, lactose intolerance as well as Helicobacter pylori (H. pylori) infection and atrophic gastritis. Many commonly used drugs, such as bile acid sequestrants, ferrous sulphate, sucralfate, calcium carbonate, aluminium-containing antacids, phosphate binders, raloxifene and proton-pump inhibitors, have also been shown to interfere with the absorption of levothyroxine.

Authors+Show Affiliations

Department of Endocrinology, VA Greater Los Angeles Healthcare System, Endocrinology 111D, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA. liwanpol@cshs.orgNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19942153

Citation

Liwanpo, Llanyee, and Jerome M. Hershman. "Conditions and Drugs Interfering With Thyroxine Absorption." Best Practice & Research. Clinical Endocrinology & Metabolism, vol. 23, no. 6, 2009, pp. 781-92.
Liwanpo L, Hershman JM. Conditions and drugs interfering with thyroxine absorption. Best Pract Res Clin Endocrinol Metab. 2009;23(6):781-92.
Liwanpo, L., & Hershman, J. M. (2009). Conditions and drugs interfering with thyroxine absorption. Best Practice & Research. Clinical Endocrinology & Metabolism, 23(6), pp. 781-92. doi:10.1016/j.beem.2009.06.006.
Liwanpo L, Hershman JM. Conditions and Drugs Interfering With Thyroxine Absorption. Best Pract Res Clin Endocrinol Metab. 2009;23(6):781-92. PubMed PMID: 19942153.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Conditions and drugs interfering with thyroxine absorption. AU - Liwanpo,Llanyee, AU - Hershman,Jerome M, PY - 2009/11/28/entrez PY - 2009/11/28/pubmed PY - 2010/2/13/medline SP - 781 EP - 92 JF - Best practice & research. Clinical endocrinology & metabolism JO - Best Pract. Res. Clin. Endocrinol. Metab. VL - 23 IS - 6 N2 - Food, dietary fibre and espresso coffee interfere with the absorption of levothyroxine. Malabsorptive disorders reported to affect the absorption of levothyroxine include coeliac disease, inflammatory bowel disease, lactose intolerance as well as Helicobacter pylori (H. pylori) infection and atrophic gastritis. Many commonly used drugs, such as bile acid sequestrants, ferrous sulphate, sucralfate, calcium carbonate, aluminium-containing antacids, phosphate binders, raloxifene and proton-pump inhibitors, have also been shown to interfere with the absorption of levothyroxine. SN - 1878-1594 UR - https://www.unboundmedicine.com/medline/citation/19942153/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S1521-690X(09)00076-1 DB - PRIME DP - Unbound Medicine ER -