Citation
Sluik, Diewertje, et al. "Physical Activity and Mortality in Individuals With Diabetes Mellitus: a Prospective Study and Meta-analysis." Archives of Internal Medicine, vol. 172, no. 17, 2012, pp. 1285-95.
Sluik D, Buijsse B, Muckelbauer R, et al. Physical Activity and Mortality in Individuals With Diabetes Mellitus: A Prospective Study and Meta-analysis. Arch Intern Med. 2012;172(17):1285-95.
Sluik, D., Buijsse, B., Muckelbauer, R., Kaaks, R., Teucher, B., Johnsen, N. F., Tjønneland, A., Overvad, K., Ostergaard, J. N., Amiano, P., Ardanaz, E., Bendinelli, B., Pala, V., Tumino, R., Ricceri, F., Mattiello, A., Spijkerman, A. M., Monninkhof, E. M., May, A. M., ... Nöthlings, U. (2012). Physical Activity and Mortality in Individuals With Diabetes Mellitus: A Prospective Study and Meta-analysis. Archives of Internal Medicine, 172(17), 1285-95. https://doi.org/10.1001/archinternmed.2012.3130
Sluik D, et al. Physical Activity and Mortality in Individuals With Diabetes Mellitus: a Prospective Study and Meta-analysis. Arch Intern Med. 2012 Sep 24;172(17):1285-95. PubMed PMID: 22868663.
TY - JOUR
T1 - Physical Activity and Mortality in Individuals With Diabetes Mellitus: A Prospective Study and Meta-analysis.
AU - Sluik,Diewertje,
AU - Buijsse,Brian,
AU - Muckelbauer,Rebecca,
AU - Kaaks,Rudolf,
AU - Teucher,Birgit,
AU - Johnsen,Nina Føns,
AU - Tjønneland,Anne,
AU - Overvad,Kim,
AU - Ostergaard,Jane Nautrup,
AU - Amiano,Pilar,
AU - Ardanaz,Eva,
AU - Bendinelli,Benedetta,
AU - Pala,Valeria,
AU - Tumino,Rosario,
AU - Ricceri,Fulvio,
AU - Mattiello,Amalia,
AU - Spijkerman,Annemieke M W,
AU - Monninkhof,Evelyn M,
AU - May,Anne M,
AU - Franks,Paul W,
AU - Nilsson,Peter M,
AU - Wennberg,Patrik,
AU - Rolandsson,Olov,
AU - Fagherazzi,Guy,
AU - Boutron-Ruault,Marie-Christine,
AU - Clavel-Chapelon,Françoise,
AU - Castaño,José María Huerta,
AU - Gallo,Valentina,
AU - Boeing,Heiner,
AU - Nöthlings,Ute,
PY - 2012/8/8/entrez
PY - 2012/8/8/pubmed
PY - 2012/8/8/medline
SP - 1285
EP - 95
JF - Archives of internal medicine
JO - Arch Intern Med
VL - 172
IS - 17
N2 - BACKGROUND Physical activity (PA) is considered a cornerstone of diabetes mellitus management to prevent complications, but conclusive evidence is lacking. METHODS This prospective cohort study and meta-analysis of existing studies investigated the association between PA and mortality in individuals with diabetes. In the EPIC study (European Prospective Investigation Into Cancer and Nutrition), a cohort was defined of 5859 individuals with diabetes at baseline. Associations of leisure-time and total PA and walking with cardiovascular disease (CVD) and total mortality were studied using multivariable Cox proportional hazards regression models. Fixed- and random-effects meta-analyses of prospective studies published up to December 2010 were pooled with inverse variance weighting. RESULTS In the prospective analysis, total PA was associated with lower risk of CVD and total mortality. Compared with physically inactive persons, the lowest mortality risk was observed in moderately active persons: hazard ratios were 0.62 (95% CI, 0.49-0.78) for total mortality and 0.51 (95% CI, 0.32-0.81) for CVD mortality. Leisure-time PA was associated with lower total mortality risk, and walking was associated with lower CVD mortality risk. In the meta-analysis, the pooled random-effects hazard ratio from 5 studies for high vs low total PA and all-cause mortality was 0.60 (95% CI, 0.49-0.73). CONCLUSIONS Higher levels of PA were associated with lower mortality risk in individuals with diabetes. Even those undertaking moderate amounts of activity were at appreciably lower risk for early death compared with inactive persons. These findings provide empirical evidence supporting the widely shared view that persons with diabetes should engage in regular PA.
SN - 1538-3679
UR - https://www.unboundmedicine.com/medline/citation/22868663/full_citation
DB - PRIME
DP - Unbound Medicine
ER -
