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Relation of moderate alcohol consumption and risk of systemic hypertension in women.

Abstract

The relation between alcohol consumption and the risk of development of hypertension was studied among 58,218 US female registered nurses aged 39 to 59 years who were free of diagnosed systemic hypertension and other major diseases. In 1980, all of these women completed an independently validated dietary questionnaire, which included use of alcoholic beverages. During 4 years of follow-up, 3,275 women reported an initial diagnosis of hypertension; validity of the self-report measure was demonstrated in a subsample. When compared to nondrinkers, women drinking 20 to 34 g of alcohol per day (about 2 or 3 drinks) had a significantly elevated relative risk of 1.4; the 95% confidence interval (CI) was 1.2 to 1.7 after adjustment for age and Quetelet's index. For women consuming greater than 35 g/day, the relative risk was 1.9 (95% CI 1.6 to 2.2). Adjustment for smoking and dietary variables did not alter these results. Independent significant associations were observed for the consumption of beer, wine and liquor. These prospective data suggest that alcohol intake of up to about 20 g/day does not increase the risk of hypertension among women, but beyond this level, the risk increases progressively.

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  • Authors+Show Affiliations

    ,

    Department of Epidemiology, Erasmus University School of Medicine, Rotterdam, The Netherlands.

    , , , , , , ,

    Source

    The American journal of cardiology 65:9 1990 Mar 01 pg 633-7

    MeSH

    Adult
    Alcohol Drinking
    Cohort Studies
    Female
    Humans
    Hypertension
    Middle Aged
    Prospective Studies
    Risk Factors
    Surveys and Questionnaires
    United States

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    2309634

    Citation

    Witteman, J C., et al. "Relation of Moderate Alcohol Consumption and Risk of Systemic Hypertension in Women." The American Journal of Cardiology, vol. 65, no. 9, 1990, pp. 633-7.
    Witteman JC, Willett WC, Stampfer MJ, et al. Relation of moderate alcohol consumption and risk of systemic hypertension in women. Am J Cardiol. 1990;65(9):633-7.
    Witteman, J. C., Willett, W. C., Stampfer, M. J., Colditz, G. A., Kok, F. J., Sacks, F. M., ... Hennekens, C. H. (1990). Relation of moderate alcohol consumption and risk of systemic hypertension in women. The American Journal of Cardiology, 65(9), pp. 633-7.
    Witteman JC, et al. Relation of Moderate Alcohol Consumption and Risk of Systemic Hypertension in Women. Am J Cardiol. 1990 Mar 1;65(9):633-7. PubMed PMID: 2309634.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Relation of moderate alcohol consumption and risk of systemic hypertension in women. AU - Witteman,J C, AU - Willett,W C, AU - Stampfer,M J, AU - Colditz,G A, AU - Kok,F J, AU - Sacks,F M, AU - Speizer,F E, AU - Rosner,B, AU - Hennekens,C H, PY - 1990/3/1/pubmed PY - 1990/3/1/medline PY - 1990/3/1/entrez SP - 633 EP - 7 JF - The American journal of cardiology JO - Am. J. Cardiol. VL - 65 IS - 9 N2 - The relation between alcohol consumption and the risk of development of hypertension was studied among 58,218 US female registered nurses aged 39 to 59 years who were free of diagnosed systemic hypertension and other major diseases. In 1980, all of these women completed an independently validated dietary questionnaire, which included use of alcoholic beverages. During 4 years of follow-up, 3,275 women reported an initial diagnosis of hypertension; validity of the self-report measure was demonstrated in a subsample. When compared to nondrinkers, women drinking 20 to 34 g of alcohol per day (about 2 or 3 drinks) had a significantly elevated relative risk of 1.4; the 95% confidence interval (CI) was 1.2 to 1.7 after adjustment for age and Quetelet's index. For women consuming greater than 35 g/day, the relative risk was 1.9 (95% CI 1.6 to 2.2). Adjustment for smoking and dietary variables did not alter these results. Independent significant associations were observed for the consumption of beer, wine and liquor. These prospective data suggest that alcohol intake of up to about 20 g/day does not increase the risk of hypertension among women, but beyond this level, the risk increases progressively. SN - 0002-9149 UR - https://www.unboundmedicine.com/medline/citation/2309634/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/0002-9149(90)91043-6 DB - PRIME DP - Unbound Medicine ER -