Prime

Type your tag names separated by a space and hit enter

Chronic kidney disease as a coronary artery disease risk equivalent.

Abstract

Chronic kidney disease (CKD) is associated with accelerated cardiovascular disease (CVD) risk and a higher CVD event rate. Substantial data from prospective cohort studies support the concept that dialysis patients as well as those with advanced stage (stages 3-5) CKD are associated with an increased risk for all-cause and cardiovascular mortality. The risk for coronary artery disease (CAD) increases exponentially with declining kidney function, i.e., stage 3 or higher CKD. Indeed, CVD accounts for more than 50 % of deaths in patients with CKD. CKD patients are more likely to die of CVD than to progress to end stage kidney disease. This increase in CV risk is commonly attributed to co-existence of numerous traditional and nontraditional risk factors for the development of CVD that frequently accompany reduced kidney function. Therefore, CKD itself is now considered an independent CVD risk factor and a coronary artery disease (CAD) equivalent for all-cause mortality. All patients at risk for CAD should be evaluated for kidney disease. Treatments used for management of established CAD might have similar benefits for patients with concomitant CKD.

Links

  • Publisher Full Text
  • Authors

    ,

    Source

    Current cardiology reports 15:3 2013 Mar pg 340

    MeSH

    Coronary Artery Disease
    Humans
    Meta-Analysis as Topic
    Renal Insufficiency, Chronic
    Risk Factors

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    23338722

    Citation

    TY - JOUR T1 - Chronic kidney disease as a coronary artery disease risk equivalent. AU - Briasoulis,Alexandrios, AU - Bakris,George L, PY - 2013/1/23/entrez PY - 2013/1/23/pubmed PY - 2013/6/29/medline SP - 340 EP - 340 JF - Current cardiology reports JO - Curr Cardiol Rep VL - 15 IS - 3 N2 - Chronic kidney disease (CKD) is associated with accelerated cardiovascular disease (CVD) risk and a higher CVD event rate. Substantial data from prospective cohort studies support the concept that dialysis patients as well as those with advanced stage (stages 3-5) CKD are associated with an increased risk for all-cause and cardiovascular mortality. The risk for coronary artery disease (CAD) increases exponentially with declining kidney function, i.e., stage 3 or higher CKD. Indeed, CVD accounts for more than 50 % of deaths in patients with CKD. CKD patients are more likely to die of CVD than to progress to end stage kidney disease. This increase in CV risk is commonly attributed to co-existence of numerous traditional and nontraditional risk factors for the development of CVD that frequently accompany reduced kidney function. Therefore, CKD itself is now considered an independent CVD risk factor and a coronary artery disease (CAD) equivalent for all-cause mortality. All patients at risk for CAD should be evaluated for kidney disease. Treatments used for management of established CAD might have similar benefits for patients with concomitant CKD. SN - 1534-3170 UR - https://www.unboundmedicine.com/medline/citation/23338722/full_citation L2 - http://dx.doi.org/10.1007/s11886-012-0340-4 ER -