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Association of antioxidants with allergic rhinitis in children from seoul.

Abstract

PURPOSE

The prevalence of allergic diseases has risen over the last few decades. Many factors, including environmental factors such as those related to diet, have been considered. Among dietary factors, intake of antioxidant-related nutrients has been associated with the risk of allergic disease. We investigated the association of antioxidant nutritional status with allergic rhinitis (AR) in Korean schoolchildren aged 6-12 years.

METHODS

Subjects were 4,554 children in Seoul, Korea. The risk of allergic disease was measured using the Korean version of the International Study of Asthma and Allergies in Childhood, and dietary intake was measured by a semi-quantitative food frequency questionnaire. Intake of vitamins A (including retinol and β-carotene), C, and E was used in the analysis.

RESULTS

Vitamin C intake was negatively associated with an increased risk of current symptoms (adjusted odds ratio, 0.886; 95% confidence interval, 0.806-0.973). There was no association between AR and intake of vitamin A, retinol, β-carotene, or vitamin E. Total serum IgE level and sensitization to allergen did not differ according to nutrient intake.

CONCLUSIONS

The group of children with increased vitamin C consumption had fewer AR symptoms, despite the lack of a difference in total serum IgE level or allergen sensitization. These findings suggest that nutrient intake, especially that of vitamin C, influences AR symptoms.

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  • Authors+Show Affiliations

    ,

    Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea.

    , , , , , , , , , , , ,

    Source

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    23450181

    Citation

    Seo, Ju-Hee, et al. "Association of Antioxidants With Allergic Rhinitis in Children From Seoul." Allergy, Asthma & Immunology Research, vol. 5, no. 2, 2013, pp. 81-7.
    Seo JH, Kwon SO, Lee SY, et al. Association of antioxidants with allergic rhinitis in children from seoul. Allergy Asthma Immunol Res. 2013;5(2):81-7.
    Seo, J. H., Kwon, S. O., Lee, S. Y., Kim, H. Y., Kwon, J. W., Kim, B. J., ... Hong, S. J. (2013). Association of antioxidants with allergic rhinitis in children from seoul. Allergy, Asthma & Immunology Research, 5(2), pp. 81-7. doi:10.4168/aair.2013.5.2.81.
    Seo JH, et al. Association of Antioxidants With Allergic Rhinitis in Children From Seoul. Allergy Asthma Immunol Res. 2013;5(2):81-7. PubMed PMID: 23450181.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Association of antioxidants with allergic rhinitis in children from seoul. AU - Seo,Ju-Hee, AU - Kwon,Sung-Ok, AU - Lee,So-Yeon, AU - Kim,Hyung Young, AU - Kwon,Ji-Won, AU - Kim,Byoung-Ju, AU - Yu,Jinho, AU - Kim,Hyo-Bin, AU - Kim,Woo Kyung, AU - Jang,Gwang Cheon, AU - Song,Dae Jin, AU - Shim,Jung Yeon, AU - Oh,Se-Young, AU - Hong,Soo-Jong, Y1 - 2012/11/07/ PY - 2011/10/17/received PY - 2012/05/11/revised PY - 2012/06/26/accepted PY - 2013/3/2/entrez PY - 2013/3/2/pubmed PY - 2013/3/2/medline KW - Allergic rhinitis KW - antioxidant KW - vitamin C SP - 81 EP - 7 JF - Allergy, asthma & immunology research JO - Allergy Asthma Immunol Res VL - 5 IS - 2 N2 - PURPOSE: The prevalence of allergic diseases has risen over the last few decades. Many factors, including environmental factors such as those related to diet, have been considered. Among dietary factors, intake of antioxidant-related nutrients has been associated with the risk of allergic disease. We investigated the association of antioxidant nutritional status with allergic rhinitis (AR) in Korean schoolchildren aged 6-12 years. METHODS: Subjects were 4,554 children in Seoul, Korea. The risk of allergic disease was measured using the Korean version of the International Study of Asthma and Allergies in Childhood, and dietary intake was measured by a semi-quantitative food frequency questionnaire. Intake of vitamins A (including retinol and β-carotene), C, and E was used in the analysis. RESULTS: Vitamin C intake was negatively associated with an increased risk of current symptoms (adjusted odds ratio, 0.886; 95% confidence interval, 0.806-0.973). There was no association between AR and intake of vitamin A, retinol, β-carotene, or vitamin E. Total serum IgE level and sensitization to allergen did not differ according to nutrient intake. CONCLUSIONS: The group of children with increased vitamin C consumption had fewer AR symptoms, despite the lack of a difference in total serum IgE level or allergen sensitization. These findings suggest that nutrient intake, especially that of vitamin C, influences AR symptoms. SN - 2092-7355 UR - https://www.unboundmedicine.com/medline/citation/23450181/full_citation L2 - https://e-aair.org/DOIx.php?id=10.4168/aair.2013.5.2.81 DB - PRIME DP - Unbound Medicine ER -