Tags

Type your tag names separated by a space and hit enter

Dietary habits are related to outcomes in patients with advanced heart failure awaiting heart transplantation.
J Card Fail 2013; 19(4):240-50JC

Abstract

BACKGROUND

Empirical evidence supporting the benefits of dietary recommendations for patients with advanced heart failure is scarce. We prospectively evaluated the relation of dietary habits to pre-transplant clinical outcomes in the multisite observational Waiting for a New Heart Study.

METHODS AND RESULTS

A total of 318 heart transplant candidates (82% male, age 53 ± 11 years) completed a Food Frequency Questionnaire (foods high in salt, saturated fats, poly-/monounsaturated fats [PUFA+MUFA], fruit/vegetables/legumes, and fluid intake) at time of waitlisting. Cox proportional hazard models controlling for heart failure severity (eg, Heart Failure Survival Score, creatinine) estimated cause-specific hazard ratios (HRs) associated with each dietary habit individually, and with all dietary habits entered simultaneously. During follow-up (median 338 days, range 13-1,394), 54 patients died, 151 received transplants (110 in high-urgency status, 41 electively), and 45 became delisted (15 deteriorated, 30 improved). Two robust findings emerged: Frequent intake of salty foods, which correlated positively with saturated fat and fluid intake, was associated with transplantation in high-urgency status (HR 2.90, 95% confidence interval [CI] 1.55-5.42); and frequent intake of foods rich in PUFA+MUFA reduced the risk for death/deterioration (HR 0.49, 95% CI 0.26-0.92).

CONCLUSIONS

These results support the importance of dietary habits for the prognosis of patients listed for heart transplantation, independently from heart failure severity.

Authors+Show Affiliations

Department of Psychology, Johannes Gutenberg University, Mainz, Germany. spaderna@uni-wuppertal.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

23582090

Citation

Spaderna, Heike, et al. "Dietary Habits Are Related to Outcomes in Patients With Advanced Heart Failure Awaiting Heart Transplantation." Journal of Cardiac Failure, vol. 19, no. 4, 2013, pp. 240-50.
Spaderna H, Zahn D, Pretsch J, et al. Dietary habits are related to outcomes in patients with advanced heart failure awaiting heart transplantation. J Card Fail. 2013;19(4):240-50.
Spaderna, H., Zahn, D., Pretsch, J., Connor, S. L., Zittermann, A., Schulze Schleithoff, S., ... Weidner, G. (2013). Dietary habits are related to outcomes in patients with advanced heart failure awaiting heart transplantation. Journal of Cardiac Failure, 19(4), pp. 240-50. doi:10.1016/j.cardfail.2013.02.004.
Spaderna H, et al. Dietary Habits Are Related to Outcomes in Patients With Advanced Heart Failure Awaiting Heart Transplantation. J Card Fail. 2013;19(4):240-50. PubMed PMID: 23582090.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary habits are related to outcomes in patients with advanced heart failure awaiting heart transplantation. AU - Spaderna,Heike, AU - Zahn,Daniela, AU - Pretsch,Johanna, AU - Connor,Sonja L, AU - Zittermann,Armin, AU - Schulze Schleithoff,Stefanie, AU - Bramstedt,Katrina A, AU - Smits,Jacqueline M A, AU - Weidner,Gerdi, PY - 2012/06/29/received PY - 2013/02/16/revised PY - 2013/02/27/accepted PY - 2013/4/16/entrez PY - 2013/4/16/pubmed PY - 2014/1/22/medline SP - 240 EP - 50 JF - Journal of cardiac failure JO - J. Card. Fail. VL - 19 IS - 4 N2 - BACKGROUND: Empirical evidence supporting the benefits of dietary recommendations for patients with advanced heart failure is scarce. We prospectively evaluated the relation of dietary habits to pre-transplant clinical outcomes in the multisite observational Waiting for a New Heart Study. METHODS AND RESULTS: A total of 318 heart transplant candidates (82% male, age 53 ± 11 years) completed a Food Frequency Questionnaire (foods high in salt, saturated fats, poly-/monounsaturated fats [PUFA+MUFA], fruit/vegetables/legumes, and fluid intake) at time of waitlisting. Cox proportional hazard models controlling for heart failure severity (eg, Heart Failure Survival Score, creatinine) estimated cause-specific hazard ratios (HRs) associated with each dietary habit individually, and with all dietary habits entered simultaneously. During follow-up (median 338 days, range 13-1,394), 54 patients died, 151 received transplants (110 in high-urgency status, 41 electively), and 45 became delisted (15 deteriorated, 30 improved). Two robust findings emerged: Frequent intake of salty foods, which correlated positively with saturated fat and fluid intake, was associated with transplantation in high-urgency status (HR 2.90, 95% confidence interval [CI] 1.55-5.42); and frequent intake of foods rich in PUFA+MUFA reduced the risk for death/deterioration (HR 0.49, 95% CI 0.26-0.92). CONCLUSIONS: These results support the importance of dietary habits for the prognosis of patients listed for heart transplantation, independently from heart failure severity. SN - 1532-8414 UR - https://www.unboundmedicine.com/medline/citation/23582090/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S1071-9164(13)00067-5 DB - PRIME DP - Unbound Medicine ER -