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The association between insomnia and cardiovascular diseases.

Abstract

Insomnia, the most common sleep complaint in the general population, is defined by difficulty initiating or maintaining sleep, or nonrestorative sleep, accompanied by some form of daytime impairment. In the current review, we present an overview of recent studies on the association between insomnia and cardiovascular disease. It can be concluded that there is growing evidence for the hypothesis that insomnia is associated with an increased risk for cardiovascular disease independently of classic coronary risk factors. Furthermore, insomnia is likely to be associated with hypertension and elevated resting heart rate, both known to lead to cardiovascular disease. However, the existing evidence is not totally consistent and most findings have not been replicated unequivocally. The major limitations of the cited studies include the failure to use state-of-the-art criteria for insomnia diagnosis, the failure to control for depression, and the use of hypnotic medication and sleep apnea as potential confounders. However, the results suggest that insomnia is associated with an increased risk for cardiovascular disease mediated by hypertension or elevated resting heart rate. Consequently, more effort should be dedicated to cope with the high prevalence of insomnia in the general population.

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  • Authors+Show Affiliations

    ,

    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany.

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    Source

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    23616699

    Citation

    Spiegelhalder, Kai, et al. "The Association Between Insomnia and Cardiovascular Diseases." Nature and Science of Sleep, vol. 2, 2010, pp. 71-8.
    Spiegelhalder K, Scholtes C, Riemann D. The association between insomnia and cardiovascular diseases. Nat Sci Sleep. 2010;2:71-8.
    Spiegelhalder, K., Scholtes, C., & Riemann, D. (2010). The association between insomnia and cardiovascular diseases. Nature and Science of Sleep, 2, pp. 71-8.
    Spiegelhalder K, Scholtes C, Riemann D. The Association Between Insomnia and Cardiovascular Diseases. Nat Sci Sleep. 2010;2:71-8. PubMed PMID: 23616699.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The association between insomnia and cardiovascular diseases. AU - Spiegelhalder,Kai, AU - Scholtes,Cathy, AU - Riemann,Dieter, Y1 - 2010/05/04/ PY - 2013/4/26/entrez PY - 2010/1/1/pubmed PY - 2010/1/1/medline KW - cardiovascular mortality KW - heart rate KW - heart rate variability KW - hypertension SP - 71 EP - 8 JF - Nature and science of sleep JO - Nat Sci Sleep VL - 2 N2 - Insomnia, the most common sleep complaint in the general population, is defined by difficulty initiating or maintaining sleep, or nonrestorative sleep, accompanied by some form of daytime impairment. In the current review, we present an overview of recent studies on the association between insomnia and cardiovascular disease. It can be concluded that there is growing evidence for the hypothesis that insomnia is associated with an increased risk for cardiovascular disease independently of classic coronary risk factors. Furthermore, insomnia is likely to be associated with hypertension and elevated resting heart rate, both known to lead to cardiovascular disease. However, the existing evidence is not totally consistent and most findings have not been replicated unequivocally. The major limitations of the cited studies include the failure to use state-of-the-art criteria for insomnia diagnosis, the failure to control for depression, and the use of hypnotic medication and sleep apnea as potential confounders. However, the results suggest that insomnia is associated with an increased risk for cardiovascular disease mediated by hypertension or elevated resting heart rate. Consequently, more effort should be dedicated to cope with the high prevalence of insomnia in the general population. SN - 1179-1608 UR - https://www.unboundmedicine.com/medline/citation/23616699/full_citation L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23616699/ DB - PRIME DP - Unbound Medicine ER -