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Pycnogenol® in chronic venous insufficiency and related venous disorders.
Phytother Res. 2014 Mar; 28(3):348-62.PR

Abstract

The present review provides an update of the biological profile of Pycnogenol in the light of its use in the treatment of chronic venous insufficiency (CVI) and related venous disorders such as deep vein thrombosis (DVT), post-thrombotic syndrome, long haul air-travel-related leg oedema, venous ulcers and acute haemorrhoids. Pycnogenol is a French maritime pine bark extract produced from the outer bark of Pinus pinaster Ait. subsp. atlantica. Its strong antioxidant, anti-inflammatory and vasodilator activities, antithrombotic effects and collagen stabilizing properties make it uniquely able to target the multi facet pathophysiology of CVI and related venous disorders. Clinical studies have shown that it can reduce oedema of the legs in CVI, reduce the incidence of deep venous thrombosis during long haul flights and enhance the healing of venous ulcers and haemorrhoidal episodes by topical application and/or oral administration. This review highlights clinical research findings on the safety, compliance and efficacy of Pycnogenol, including its use in combination products.

Authors+Show Affiliations

Horphag Research, Geneva, Switzerland.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23775628

Citation

Gulati, Om P.. "Pycnogenol® in Chronic Venous Insufficiency and Related Venous Disorders." Phytotherapy Research : PTR, vol. 28, no. 3, 2014, pp. 348-62.
Gulati OP. Pycnogenol® in chronic venous insufficiency and related venous disorders. Phytother Res. 2014;28(3):348-62.
Gulati, O. P. (2014). Pycnogenol® in chronic venous insufficiency and related venous disorders. Phytotherapy Research : PTR, 28(3), 348-62. https://doi.org/10.1002/ptr.5019
Gulati OP. Pycnogenol® in Chronic Venous Insufficiency and Related Venous Disorders. Phytother Res. 2014;28(3):348-62. PubMed PMID: 23775628.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pycnogenol® in chronic venous insufficiency and related venous disorders. A1 - Gulati,Om P, Y1 - 2013/06/15/ PY - 2013/04/17/received PY - 2013/05/14/accepted PY - 2013/6/19/entrez PY - 2013/6/19/pubmed PY - 2014/5/27/medline KW - Pycnogenol KW - chronic venous insufficiency KW - deep vein thrombosis KW - food supplement KW - haemorrhoids KW - long-haul air travel KW - nutraceutical KW - post-thrombotic syndrome KW - venous health KW - venous ulcers SP - 348 EP - 62 JF - Phytotherapy research : PTR JO - Phytother Res VL - 28 IS - 3 N2 - The present review provides an update of the biological profile of Pycnogenol in the light of its use in the treatment of chronic venous insufficiency (CVI) and related venous disorders such as deep vein thrombosis (DVT), post-thrombotic syndrome, long haul air-travel-related leg oedema, venous ulcers and acute haemorrhoids. Pycnogenol is a French maritime pine bark extract produced from the outer bark of Pinus pinaster Ait. subsp. atlantica. Its strong antioxidant, anti-inflammatory and vasodilator activities, antithrombotic effects and collagen stabilizing properties make it uniquely able to target the multi facet pathophysiology of CVI and related venous disorders. Clinical studies have shown that it can reduce oedema of the legs in CVI, reduce the incidence of deep venous thrombosis during long haul flights and enhance the healing of venous ulcers and haemorrhoidal episodes by topical application and/or oral administration. This review highlights clinical research findings on the safety, compliance and efficacy of Pycnogenol, including its use in combination products. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/23775628/full_citation L2 - https://doi.org/10.1002/ptr.5019 DB - PRIME DP - Unbound Medicine ER -