TY - JOUR T1 - Influence of flavonoid-rich fruit and vegetable intake on diabetic retinopathy and diabetes-related biomarkers. AU - Mahoney,Sara E, AU - Loprinzi,Paul D, Y1 - 2014/06/21/ PY - 2014/01/31/received PY - 2014/06/09/revised PY - 2014/06/16/accepted PY - 2014/7/25/entrez PY - 2014/7/25/pubmed PY - 2015/8/25/medline KW - Diabetic retinopathy KW - Flavonoid KW - Fruit and vegetable consumption KW - Glycemic control KW - Inflammation SP - 767 EP - 71 JF - Journal of diabetes and its complications JO - J Diabetes Complications VL - 28 IS - 6 N2 - OBJECTIVE: (1) Determine the relationship between dietary flavonoid-rich fruit and vegetable consumption on diabetes-related biomarkers (e.g., HgbA1c) and diabetic retinopathy. METHODS: Data from 381 participants with diabetes from the NHANES 2003-2006 were analyzed. Blood samples were taken to measure C-reactive protein (CRP), HgbA1C, and fasting glucose and insulin. Diabetic retinopathy was assessed from a retinal imaging exam. A high-flavonoid fruit and vegetable consumption (HFVC) index variable was created from a food frequency questionnaire (FFQ). RESULTS: After adjustments, greater HFVC was associated (p<0.05) with lower levels of CRP (β=-0.005), HgbA1C (β=-0.005) and glucose (β=-0.59), with greater HFVC reducing the odds of having diabetic retinopathy by 30%. CONCLUSION: Adults with diabetes consuming more flavonoid-rich fruits and vegetables had lower degrees of inflammation, better glycemic control, and reduced odds of diabetic retinopathy. SN - 1873-460X UR - https://www.unboundmedicine.com/medline/citation/25055729/full_citation DB - PRIME DP - Unbound Medicine ER -