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Correlation between the severity and type of acne lesions with serum zinc levels in patients with acne vulgaris.

Abstract

Acne vulgaris is the most common cutaneous disorder affecting adolescents and young adults. Some studies have reported an association between serum zinc levels and acne vulgaris. We aimed to evaluate the serum zinc level in patients with acne vulgaris and compare it with healthy controls. One hundred patients with acne vulgaris and 100 healthy controls were referred to our clinic. Acne severity was classified according to Global Acne Grading System (GAGS). Atomic absorption spectrophotometry was used to measure serum zinc levels. Mean serum level of zinc in acne patients and controls was 81.31 ± 17.63 μg/dl and 82.63 ± 17.49 μg/dl, respectively. Although the mean serum zinc level was lower in acne group, it was not statistically significant (P = 0.598). There was a correlation between serum zinc levels with severity and type of acne lesions. The results of our study suggest that zinc levels may be related to the severity and type of acne lesions in patients with acne vulgaris. Relative decrease of serum zinc level in acne patients suggests a role for zinc in the pathogenesis of acne vulgaris.

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  • Authors+Show Affiliations

    ,

    Department of Dermatology, Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil 5618953141, Iran.

    ,

    Department of Midwifery, Islamic Azad University, Ardabil branch, Ardabil 5615731567, Iran.

    ,

    Department of Internal Medicine, Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil 5618953141, Iran.

    Department of Dermatology, Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil 5618953141, Iran.

    Source

    BioMed research international 2014: 2014 pg 474108

    MeSH

    Acne Vulgaris
    Adolescent
    Adult
    Case-Control Studies
    Female
    Humans
    Male
    Middle Aged
    Young Adult
    Zinc

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    25157359

    Citation

    Rostami Mogaddam, Majid, et al. "Correlation Between the Severity and Type of Acne Lesions With Serum Zinc Levels in Patients With Acne Vulgaris." BioMed Research International, vol. 2014, 2014, p. 474108.
    Rostami Mogaddam M, Safavi Ardabili N, Maleki N, et al. Correlation between the severity and type of acne lesions with serum zinc levels in patients with acne vulgaris. Biomed Res Int. 2014;2014:474108.
    Rostami Mogaddam, M., Safavi Ardabili, N., Maleki, N., & Soflaee, M. (2014). Correlation between the severity and type of acne lesions with serum zinc levels in patients with acne vulgaris. BioMed Research International, 2014, p. 474108. doi:10.1155/2014/474108.
    Rostami Mogaddam M, et al. Correlation Between the Severity and Type of Acne Lesions With Serum Zinc Levels in Patients With Acne Vulgaris. Biomed Res Int. 2014;2014:474108. PubMed PMID: 25157359.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Correlation between the severity and type of acne lesions with serum zinc levels in patients with acne vulgaris. AU - Rostami Mogaddam,Majid, AU - Safavi Ardabili,Nastaran, AU - Maleki,Nasrollah, AU - Soflaee,Maedeh, Y1 - 2014/07/24/ PY - 2014/02/06/received PY - 2014/07/14/accepted PY - 2014/8/27/entrez PY - 2014/8/27/pubmed PY - 2015/11/3/medline SP - 474108 EP - 474108 JF - BioMed research international JO - Biomed Res Int VL - 2014 N2 - Acne vulgaris is the most common cutaneous disorder affecting adolescents and young adults. Some studies have reported an association between serum zinc levels and acne vulgaris. We aimed to evaluate the serum zinc level in patients with acne vulgaris and compare it with healthy controls. One hundred patients with acne vulgaris and 100 healthy controls were referred to our clinic. Acne severity was classified according to Global Acne Grading System (GAGS). Atomic absorption spectrophotometry was used to measure serum zinc levels. Mean serum level of zinc in acne patients and controls was 81.31 ± 17.63 μg/dl and 82.63 ± 17.49 μg/dl, respectively. Although the mean serum zinc level was lower in acne group, it was not statistically significant (P = 0.598). There was a correlation between serum zinc levels with severity and type of acne lesions. The results of our study suggest that zinc levels may be related to the severity and type of acne lesions in patients with acne vulgaris. Relative decrease of serum zinc level in acne patients suggests a role for zinc in the pathogenesis of acne vulgaris. SN - 2314-6141 UR - https://www.unboundmedicine.com/medline/citation/25157359/full_citation L2 - https://dx.doi.org/10.1155/2014/474108 DB - PRIME DP - Unbound Medicine ER -