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Gout: a review of nonmodifiable and modifiable risk factors.

Abstract

Gout is a common inflammatory arthritis triggered by the crystallization of uric acid within the joints. Gout affects millions worldwide and has an increasing prevalence. Recent research has been carried out to better qualify and quantify the risk factors predisposing individuals to gout. These can largely be broken into nonmodifiable risk factors, such as gender, age, race, and genetics, and modifiable risk factors, such as diet and lifestyle. Increasing knowledge of factors predisposing certain individuals to gout could potentially lead to improved preventive practices. This review summarizes the nonmodifiable and modifiable risk factors associated with development of gout.

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  • Authors+Show Affiliations

    ,

    Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA; Division of Rheumatology, Allergy and Immunology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address: skim62@partners.org.

    Source

    MeSH

    Age Factors
    Diet
    Female
    Genetic Predisposition to Disease
    Gout
    Humans
    Hyperuricemia
    Male
    Obesity
    Risk Factors
    Sex Factors

    Pub Type(s)

    Journal Article
    Research Support, N.I.H., Extramural
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    25437279

    Citation

    MacFarlane, Lindsey A., and Seoyoung C. Kim. "Gout: a Review of Nonmodifiable and Modifiable Risk Factors." Rheumatic Diseases Clinics of North America, vol. 40, no. 4, 2014, pp. 581-604.
    MacFarlane LA, Kim SC. Gout: a review of nonmodifiable and modifiable risk factors. Rheum Dis Clin North Am. 2014;40(4):581-604.
    MacFarlane, L. A., & Kim, S. C. (2014). Gout: a review of nonmodifiable and modifiable risk factors. Rheumatic Diseases Clinics of North America, 40(4), pp. 581-604. doi:10.1016/j.rdc.2014.07.002.
    MacFarlane LA, Kim SC. Gout: a Review of Nonmodifiable and Modifiable Risk Factors. Rheum Dis Clin North Am. 2014;40(4):581-604. PubMed PMID: 25437279.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Gout: a review of nonmodifiable and modifiable risk factors. AU - MacFarlane,Lindsey A, AU - Kim,Seoyoung C, Y1 - 2014/09/02/ PY - 2014/12/2/entrez PY - 2014/12/2/pubmed PY - 2015/7/22/medline KW - Diet KW - Genetics KW - Gout KW - Race KW - Risk factors KW - Sex SP - 581 EP - 604 JF - Rheumatic diseases clinics of North America JO - Rheum. Dis. Clin. North Am. VL - 40 IS - 4 N2 - Gout is a common inflammatory arthritis triggered by the crystallization of uric acid within the joints. Gout affects millions worldwide and has an increasing prevalence. Recent research has been carried out to better qualify and quantify the risk factors predisposing individuals to gout. These can largely be broken into nonmodifiable risk factors, such as gender, age, race, and genetics, and modifiable risk factors, such as diet and lifestyle. Increasing knowledge of factors predisposing certain individuals to gout could potentially lead to improved preventive practices. This review summarizes the nonmodifiable and modifiable risk factors associated with development of gout. SN - 1558-3163 UR - https://www.unboundmedicine.com/medline/citation/25437279/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0889-857X(14)00063-5 DB - PRIME DP - Unbound Medicine ER -