Tags

Type your tag names separated by a space and hit enter

Dietary agents for prevention and treatment of lung cancer.

Abstract

Lung cancer is a prominent cause of cancer-associated mortality worldwide. The main reason for high mortality due to lung cancer is attributable to the fact that the diagnosis is generally made when it has spread beyond a curable stage and cannot be treated surgically or with radiation therapy. Therefore, new approaches like dietary modifications could be extremely useful in reducing lung cancer incidences. Several fruits and vegetables offer a variety of bioactive compounds to afford protection against several diseases, including lung cancer. A number of research studies involving dietary agents provide strong evidence for their role in the prevention and treatment of lung cancer, and have identified their molecular mechanisms of action and potential targets. In this review article, we summarize data from in-vitro and in-vivo studies and where available, in clinical trials, on the effects of some of the most promising dietary agents against lung cancer.

Links

  • PMC Free PDF
  • PMC Free Full Text
  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA.

    Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA. Electronic address: hmukhtar@wisc.edu.

    Source

    Cancer letters 359:2 2015 Apr 10 pg 155-64

    MeSH

    Adenocarcinoma
    Administration, Oral
    Animals
    Anticarcinogenic Agents
    Antineoplastic Agents, Phytogenic
    Catechin
    Curcumin
    Flavonoids
    Humans
    Indoles
    Isothiocyanates
    Lung Neoplasms
    Plant Extracts
    Polyphenols

    Pub Type(s)

    Journal Article
    Research Support, N.I.H., Extramural
    Review

    Language

    eng

    PubMed ID

    25644088

    Citation

    Khan, Naghma, and Hasan Mukhtar. "Dietary Agents for Prevention and Treatment of Lung Cancer." Cancer Letters, vol. 359, no. 2, 2015, pp. 155-64.
    Khan N, Mukhtar H. Dietary agents for prevention and treatment of lung cancer. Cancer Lett. 2015;359(2):155-64.
    Khan, N., & Mukhtar, H. (2015). Dietary agents for prevention and treatment of lung cancer. Cancer Letters, 359(2), pp. 155-64. doi:10.1016/j.canlet.2015.01.038.
    Khan N, Mukhtar H. Dietary Agents for Prevention and Treatment of Lung Cancer. Cancer Lett. 2015 Apr 10;359(2):155-64. PubMed PMID: 25644088.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Dietary agents for prevention and treatment of lung cancer. AU - Khan,Naghma, AU - Mukhtar,Hasan, Y1 - 2015/01/30/ PY - 2014/12/17/received PY - 2015/01/16/revised PY - 2015/01/19/accepted PY - 2015/2/4/entrez PY - 2015/2/4/pubmed PY - 2015/4/22/medline KW - Dietary agents KW - Lung cancer KW - Prevention KW - Treatment SP - 155 EP - 64 JF - Cancer letters JO - Cancer Lett. VL - 359 IS - 2 N2 - Lung cancer is a prominent cause of cancer-associated mortality worldwide. The main reason for high mortality due to lung cancer is attributable to the fact that the diagnosis is generally made when it has spread beyond a curable stage and cannot be treated surgically or with radiation therapy. Therefore, new approaches like dietary modifications could be extremely useful in reducing lung cancer incidences. Several fruits and vegetables offer a variety of bioactive compounds to afford protection against several diseases, including lung cancer. A number of research studies involving dietary agents provide strong evidence for their role in the prevention and treatment of lung cancer, and have identified their molecular mechanisms of action and potential targets. In this review article, we summarize data from in-vitro and in-vivo studies and where available, in clinical trials, on the effects of some of the most promising dietary agents against lung cancer. SN - 1872-7980 UR - https://www.unboundmedicine.com/medline/citation/25644088/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-3835(15)00072-5 DB - PRIME DP - Unbound Medicine ER -