Type your tag names separated by a space and hit enter

Omega-3 polyunsaturated fatty acids and non-communicable diseases: meta-analysis based systematic review.

Abstract

The aim of this updated systematic review is to summarize the evidence of the effect of omega-3 polyunsaturated fatty acids (n-3 PUFA) on non-communicable diseases (NCDs). Publications of meta-analysis up to August 2014 were systematically searched from PubMed, the Cochrane and EMBASE databases. N-3 PUFAs have the following beneficial effects; cardio-protective effects, reduce ischemic stroke risk in both men and women and total stroke risk in women, increase insulin sensitivity in Asians, decrease risk of breast cancer and colorectal cancer in men. However, n-3 PUFAs may have unfavourable effects on type 2 diabetes in Caucasians. In conclusion, n-3 PUFA plays a crucial role in the prevention of NCDs, however, unfavourable effects should be considered in subjects with certain clinical conditions. Cross-cultural studies on the effect of n-3 PUFA on type 2 diabetes are needed to verify why diabetic patients with different ancestries have a different response to n-3 PUFA.

Links

  • FREE Publisher Full Text
  • Authors+Show Affiliations

    Department of Food Science and Nutrition, Zhejiang University, 866 Yu-hang-tang Road, Hangzhou, 310058, China, . Email: duoli@zju.edu.cn. Department of Nutrition and Dietetics, Monash University, Melbourne, Australia. School of Public Health, Ningxia University, Ningxia, China.

    Source

    MeSH

    Breast Neoplasms
    Colorectal Neoplasms
    Diabetes Mellitus, Type 2
    Fatty Acids, Omega-3
    Female
    Health Promotion
    Heart Diseases
    Humans
    Insulin Resistance
    Male
    Risk Factors
    Stroke

    Pub Type(s)

    Journal Article
    Meta-Analysis
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    25740737

    Citation

    Li, Duo. "Omega-3 Polyunsaturated Fatty Acids and Non-communicable Diseases: Meta-analysis Based Systematic Review." Asia Pacific Journal of Clinical Nutrition, vol. 24, no. 1, 2015, pp. 10-5.
    Li D. Omega-3 polyunsaturated fatty acids and non-communicable diseases: meta-analysis based systematic review. Asia Pac J Clin Nutr. 2015;24(1):10-5.
    Li, D. (2015). Omega-3 polyunsaturated fatty acids and non-communicable diseases: meta-analysis based systematic review. Asia Pacific Journal of Clinical Nutrition, 24(1), pp. 10-5. doi:10.6133/apjcn.2015.24.1.21.
    Li D. Omega-3 Polyunsaturated Fatty Acids and Non-communicable Diseases: Meta-analysis Based Systematic Review. Asia Pac J Clin Nutr. 2015;24(1):10-5. PubMed PMID: 25740737.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Omega-3 polyunsaturated fatty acids and non-communicable diseases: meta-analysis based systematic review. A1 - Li,Duo, PY - 2015/3/6/entrez PY - 2015/3/6/pubmed PY - 2015/4/25/medline SP - 10 EP - 5 JF - Asia Pacific journal of clinical nutrition JO - Asia Pac J Clin Nutr VL - 24 IS - 1 N2 - The aim of this updated systematic review is to summarize the evidence of the effect of omega-3 polyunsaturated fatty acids (n-3 PUFA) on non-communicable diseases (NCDs). Publications of meta-analysis up to August 2014 were systematically searched from PubMed, the Cochrane and EMBASE databases. N-3 PUFAs have the following beneficial effects; cardio-protective effects, reduce ischemic stroke risk in both men and women and total stroke risk in women, increase insulin sensitivity in Asians, decrease risk of breast cancer and colorectal cancer in men. However, n-3 PUFAs may have unfavourable effects on type 2 diabetes in Caucasians. In conclusion, n-3 PUFA plays a crucial role in the prevention of NCDs, however, unfavourable effects should be considered in subjects with certain clinical conditions. Cross-cultural studies on the effect of n-3 PUFA on type 2 diabetes are needed to verify why diabetic patients with different ancestries have a different response to n-3 PUFA. SN - 0964-7058 UR - https://www.unboundmedicine.com/medline/citation/25740737/full_citation L2 - http://apjcn.nhri.org.tw/server/APJCN/24/1/10.pdf DB - PRIME DP - Unbound Medicine ER -