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Management of patients with decompensated cirrhosis.

Abstract

During the assessment of a patient with liver disease, finding the patient has decompensated cirrhosis, as defined by the presence of jaundice, ascites, variceal haemorrhage or hepatic encephalopathy, has major implications regarding management and prevention of cirrhosis-related complications, as well as consideration for a referral for liver transplantation evaluation. Prognosis is markedly worse in patients with decompensated compared with compensated cirrhosis. In general, any patient with decompensated cirrhosis should receive evaluation and medical care by a hepatologist. Since patients frequently present with more than one facet of liver decompensation, such cases pose a complex management challenge requiring input from a multidisciplinary team and close liaison with a liver transplant centre.

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  • Authors+Show Affiliations

    Institute of Liver Studies, King's College Hospital, London, UK phillip.harrison@kcl.ac.uk.

    Source

    MeSH

    Humans
    Liver Cirrhosis
    Prognosis

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    25824076

    Citation

    Harrison, Phillip M.. "Management of Patients With Decompensated Cirrhosis." Clinical Medicine (London, England), vol. 15, no. 2, 2015, pp. 201-3.
    Harrison PM. Management of patients with decompensated cirrhosis. Clin Med (Lond). 2015;15(2):201-3.
    Harrison, P. M. (2015). Management of patients with decompensated cirrhosis. Clinical Medicine (London, England), 15(2), pp. 201-3. doi:10.7861/clinmedicine.15-2-201.
    Harrison PM. Management of Patients With Decompensated Cirrhosis. Clin Med (Lond). 2015;15(2):201-3. PubMed PMID: 25824076.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Management of patients with decompensated cirrhosis. A1 - Harrison,Phillip M, PY - 2015/4/1/entrez PY - 2015/4/1/pubmed PY - 2015/9/12/medline KW - Jaundice KW - ascites KW - hepatic encephalopathy KW - hepatorenal syndrome KW - liver transplant KW - nutrition KW - spontaneous bacterial peritonitis KW - variceal haemorrhage SP - 201 EP - 3 JF - Clinical medicine (London, England) JO - Clin Med (Lond) VL - 15 IS - 2 N2 - During the assessment of a patient with liver disease, finding the patient has decompensated cirrhosis, as defined by the presence of jaundice, ascites, variceal haemorrhage or hepatic encephalopathy, has major implications regarding management and prevention of cirrhosis-related complications, as well as consideration for a referral for liver transplantation evaluation. Prognosis is markedly worse in patients with decompensated compared with compensated cirrhosis. In general, any patient with decompensated cirrhosis should receive evaluation and medical care by a hepatologist. Since patients frequently present with more than one facet of liver decompensation, such cases pose a complex management challenge requiring input from a multidisciplinary team and close liaison with a liver transplant centre. SN - 1470-2118 UR - https://www.unboundmedicine.com/medline/citation/25824076/full_citation L2 - http://www.clinmed.rcpjournal.org/cgi/pmidlookup?view=long&pmid=25824076 DB - PRIME DP - Unbound Medicine ER -