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Magnesium in Prevention and Therapy.

Abstract

Magnesium is the fourth most abundant mineral in the body. It has been recognized as a cofactor for more than 300 enzymatic reactions, where it is crucial for adenosine triphosphate (ATP) metabolism. Magnesium is required for DNA and RNA synthesis, reproduction, and protein synthesis. Moreover, magnesium is essential for the regulation of muscular contraction, blood pressure, insulin metabolism, cardiac excitability, vasomotor tone, nerve transmission and neuromuscular conduction. Imbalances in magnesium status-primarily hypomagnesemia as it is seen more common than hypermagnesemia-might result in unwanted neuromuscular, cardiac or nervous disorders. Based on magnesium's many functions within the human body, it plays an important role in prevention and treatment of many diseases. Low levels of magnesium have been associated with a number of chronic diseases, such as Alzheimer's disease, insulin resistance and type-2 diabetes mellitus, hypertension, cardiovascular disease (e.g., stroke), migraine headaches, and attention deficit hyperactivity disorder (ADHD).

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  • Authors+Show Affiliations

    ,

    Academy of Micronutrient Medicine, Essen 45130, Germany. uwegroeber@gmx.net.

    ,

    Academy of Micronutrient Medicine, Essen 45130, Germany. Prof.schmidt.dd@t-online.de.

    Academy of Micronutrient Medicine, Essen 45130, Germany. kisters@annahospital.de. Department of Internal Medicine I, St. Anna-Hospital, Herne 44649, Germany. kisters@annahospital.de.

    Source

    Nutrients 7:9 2015 Sep 23 pg 8199-226

    MeSH

    Animals
    Dietary Supplements
    Homeostasis
    Humans
    Magnesium
    Magnesium Deficiency
    Nutritional Status
    Recommended Dietary Allowances
    Risk Factors
    Treatment Outcome

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    26404370

    Citation

    Gröber, Uwe, et al. "Magnesium in Prevention and Therapy." Nutrients, vol. 7, no. 9, 2015, pp. 8199-226.
    Gröber U, Schmidt J, Kisters K. Magnesium in Prevention and Therapy. Nutrients. 2015;7(9):8199-226.
    Gröber, U., Schmidt, J., & Kisters, K. (2015). Magnesium in Prevention and Therapy. Nutrients, 7(9), pp. 8199-226. doi:10.3390/nu7095388.
    Gröber U, Schmidt J, Kisters K. Magnesium in Prevention and Therapy. Nutrients. 2015 Sep 23;7(9):8199-226. PubMed PMID: 26404370.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Magnesium in Prevention and Therapy. AU - Gröber,Uwe, AU - Schmidt,Joachim, AU - Kisters,Klaus, Y1 - 2015/09/23/ PY - 2015/06/18/received PY - 2015/07/16/revised PY - 2015/09/11/accepted PY - 2015/9/26/entrez PY - 2015/9/26/pubmed PY - 2016/6/30/medline KW - ADHD KW - Alzheimer’s disease KW - asthma KW - cardiovascular disease KW - diabetes mellitus KW - hypomagnesemia KW - magnesium SP - 8199 EP - 226 JF - Nutrients JO - Nutrients VL - 7 IS - 9 N2 - Magnesium is the fourth most abundant mineral in the body. It has been recognized as a cofactor for more than 300 enzymatic reactions, where it is crucial for adenosine triphosphate (ATP) metabolism. Magnesium is required for DNA and RNA synthesis, reproduction, and protein synthesis. Moreover, magnesium is essential for the regulation of muscular contraction, blood pressure, insulin metabolism, cardiac excitability, vasomotor tone, nerve transmission and neuromuscular conduction. Imbalances in magnesium status-primarily hypomagnesemia as it is seen more common than hypermagnesemia-might result in unwanted neuromuscular, cardiac or nervous disorders. Based on magnesium's many functions within the human body, it plays an important role in prevention and treatment of many diseases. Low levels of magnesium have been associated with a number of chronic diseases, such as Alzheimer's disease, insulin resistance and type-2 diabetes mellitus, hypertension, cardiovascular disease (e.g., stroke), migraine headaches, and attention deficit hyperactivity disorder (ADHD). SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/26404370/full_citation L2 - http://www.mdpi.com/resolver?pii=nu7095388 DB - PRIME DP - Unbound Medicine ER -