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Advances in nutritional therapy in inflammatory bowel diseases: Review.

Abstract

Inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease are chronic, life-long, and relapsing diseases of the gastrointestinal tract. Currently, there are no complete cure possibilities, but combined pharmacological and nutritional therapy may induce remission of the disease. Malnutrition and specific nutritional deficiencies are frequent among IBD patients, so the majority of them need nutritional treatment, which not only improves the state of nutrition of the patients but has strong anti-inflammatory activity as well. Moreover, some nutrients, from early stages of life are suspected as triggering factors in the etiopathogenesis of IBD. Both parenteral and enteral nutrition is used in IBD therapy, but their practical utility in different populations and in different countries is not clearly established, and there are sometimes conflicting theories concerning the role of nutrition in IBD. This review presents the actual data from research studies on the influence of nutrition on the etiopathogenesis of IBD and the latest findings regarding its mechanisms of action. The use of both parenteral and enteral nutrition as therapeutic methods in induction and maintenance therapy in IBD treatment is also extensively discussed. Comparison of the latest research data, scientific theories concerning the role of nutrition in IBD, and different opinions about them are also presented and discussed. Additionally, some potential future perspectives for nutritional therapy are highlighted.

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  • Authors+Show Affiliations

    ,

    Andrzej Wędrychowicz, Department of Pediatrics, Gastroenterology and Nutrition, Polish-American Children's Hospital, Jagiellonian University Medical College, 30663 Krakow, Poland.

    ,

    Andrzej Wędrychowicz, Department of Pediatrics, Gastroenterology and Nutrition, Polish-American Children's Hospital, Jagiellonian University Medical College, 30663 Krakow, Poland.

    Andrzej Wędrychowicz, Department of Pediatrics, Gastroenterology and Nutrition, Polish-American Children's Hospital, Jagiellonian University Medical College, 30663 Krakow, Poland.

    Source

    World journal of gastroenterology 22:3 2016 Jan 21 pg 1045-66

    MeSH

    Body Composition
    Colitis, Ulcerative
    Crohn Disease
    Diet
    Diffusion of Innovation
    Enteral Nutrition
    Humans
    Nutritional Status
    Parenteral Nutrition
    Risk Factors
    Treatment Outcome

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    26811646

    Citation

    Wędrychowicz, Andrzej, et al. "Advances in Nutritional Therapy in Inflammatory Bowel Diseases: Review." World Journal of Gastroenterology, vol. 22, no. 3, 2016, pp. 1045-66.
    Wędrychowicz A, Zając A, Tomasik P. Advances in nutritional therapy in inflammatory bowel diseases: Review. World J Gastroenterol. 2016;22(3):1045-66.
    Wędrychowicz, A., Zając, A., & Tomasik, P. (2016). Advances in nutritional therapy in inflammatory bowel diseases: Review. World Journal of Gastroenterology, 22(3), pp. 1045-66. doi:10.3748/wjg.v22.i3.1045.
    Wędrychowicz A, Zając A, Tomasik P. Advances in Nutritional Therapy in Inflammatory Bowel Diseases: Review. World J Gastroenterol. 2016 Jan 21;22(3):1045-66. PubMed PMID: 26811646.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Advances in nutritional therapy in inflammatory bowel diseases: Review. AU - Wędrychowicz,Andrzej, AU - Zając,Andrzej, AU - Tomasik,Przemysław, PY - 2015/04/24/received PY - 2015/07/22/revised PY - 2015/09/13/accepted PY - 2016/1/27/entrez PY - 2016/1/27/pubmed PY - 2017/1/18/medline KW - Dietary factors KW - Etiology KW - Exclusive enteral nutrition KW - Induction therapy KW - Inflammatory bowel disease KW - Maintenance therapy KW - Nutritional therapy KW - Parenteral nutrition SP - 1045 EP - 66 JF - World journal of gastroenterology JO - World J. Gastroenterol. VL - 22 IS - 3 N2 - Inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease are chronic, life-long, and relapsing diseases of the gastrointestinal tract. Currently, there are no complete cure possibilities, but combined pharmacological and nutritional therapy may induce remission of the disease. Malnutrition and specific nutritional deficiencies are frequent among IBD patients, so the majority of them need nutritional treatment, which not only improves the state of nutrition of the patients but has strong anti-inflammatory activity as well. Moreover, some nutrients, from early stages of life are suspected as triggering factors in the etiopathogenesis of IBD. Both parenteral and enteral nutrition is used in IBD therapy, but their practical utility in different populations and in different countries is not clearly established, and there are sometimes conflicting theories concerning the role of nutrition in IBD. This review presents the actual data from research studies on the influence of nutrition on the etiopathogenesis of IBD and the latest findings regarding its mechanisms of action. The use of both parenteral and enteral nutrition as therapeutic methods in induction and maintenance therapy in IBD treatment is also extensively discussed. Comparison of the latest research data, scientific theories concerning the role of nutrition in IBD, and different opinions about them are also presented and discussed. Additionally, some potential future perspectives for nutritional therapy are highlighted. SN - 2219-2840 UR - https://www.unboundmedicine.com/medline/citation/26811646/full_citation L2 - http://www.wjgnet.com/1007-9327/full/v22/i3/1045.htm DB - PRIME DP - Unbound Medicine ER -