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Malnutrition: laboratory markers vs nutritional assessment.
Gastroenterol Rep (Oxf). 2016 Nov; 4(4):272-280.GR

Abstract

Malnutrition is an independent risk factor for patient morbidity and mortality and is associated with increased healthcare-related costs. However, a major dilemma exists due to lack of a unified definition for the term. Furthermore, there are no standard methods for screening and diagnosing patients with malnutrition, leading to confusion and varying practices among physicians across the world. The role of inflammation as a risk factor for malnutrition has also been recently recognized. Historically, serum proteins such as albumin and prealbumin (PAB) have been widely used by physicians to determine patient nutritional status. However, recent focus has been on an appropriate nutrition-focused physical examination (NFPE) for diagnosing malnutrition. The current consensus is that laboratory markers are not reliable by themselves but could be used as a complement to a thorough physical examination. Future studies are needed to identify serum biomarkers in order to diagnose malnutrition unaffected by inflammatory states and have the advantage of being noninvasive and relatively cost-effective. However, a thorough NFPE has an unprecedented role in diagnosing malnutrition.

Authors+Show Affiliations

Department of Gastroenterology/Hepatology, McMaster University, Hamilton, Ontario, Canada reachshishira@gmail.com.Department of Gastroenterology/Hepatology, McMaster University, Hamilton, Ontario, Canada.Department of Gastroenterology/Hepatology, McMaster University, Hamilton, Ontario, Canada.Department of Gastroenterology/Hepatology, McMaster University, Hamilton, Ontario, Canada.Department of Gastroenterology/Hepatology, McMaster University, Hamilton, Ontario, Canada.Department of Gastroenterology/Hepatology, Cleveland Clinic, Cleveland, OH, USA.Department of Gastroenterology/Hepatology, Cleveland Clinic, Cleveland, OH, USA.Department of Gastroenterology/Hepatology, Cleveland Clinic, Cleveland, OH, USA.

Pub Type(s)

Review
Journal Article

Language

eng

PubMed ID

27174435

Citation

Bharadwaj, Shishira, et al. "Malnutrition: Laboratory Markers Vs Nutritional Assessment." Gastroenterology Report, vol. 4, no. 4, 2016, pp. 272-280.
Bharadwaj S, Ginoya S, Tandon P, et al. Malnutrition: laboratory markers vs nutritional assessment. Gastroenterol Rep (Oxf). 2016;4(4):272-280.
Bharadwaj, S., Ginoya, S., Tandon, P., Gohel, T. D., Guirguis, J., Vallabh, H., Jevenn, A., & Hanouneh, I. (2016). Malnutrition: laboratory markers vs nutritional assessment. Gastroenterology Report, 4(4), 272-280.
Bharadwaj S, et al. Malnutrition: Laboratory Markers Vs Nutritional Assessment. Gastroenterol Rep (Oxf). 2016;4(4):272-280. PubMed PMID: 27174435.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Malnutrition: laboratory markers vs nutritional assessment. AU - Bharadwaj,Shishira, AU - Ginoya,Shaiva, AU - Tandon,Parul, AU - Gohel,Tushar D, AU - Guirguis,John, AU - Vallabh,Hiren, AU - Jevenn,Andrea, AU - Hanouneh,Ibrahim, Y1 - 2016/05/11/ PY - 2015/12/30/received PY - 2016/02/26/revised PY - 2016/03/16/accepted PY - 2016/5/14/pubmed PY - 2016/5/14/medline PY - 2016/5/14/entrez KW - malnutrition KW - physical examination KW - serum markers SP - 272 EP - 280 JF - Gastroenterology report JO - Gastroenterol Rep (Oxf) VL - 4 IS - 4 N2 - Malnutrition is an independent risk factor for patient morbidity and mortality and is associated with increased healthcare-related costs. However, a major dilemma exists due to lack of a unified definition for the term. Furthermore, there are no standard methods for screening and diagnosing patients with malnutrition, leading to confusion and varying practices among physicians across the world. The role of inflammation as a risk factor for malnutrition has also been recently recognized. Historically, serum proteins such as albumin and prealbumin (PAB) have been widely used by physicians to determine patient nutritional status. However, recent focus has been on an appropriate nutrition-focused physical examination (NFPE) for diagnosing malnutrition. The current consensus is that laboratory markers are not reliable by themselves but could be used as a complement to a thorough physical examination. Future studies are needed to identify serum biomarkers in order to diagnose malnutrition unaffected by inflammatory states and have the advantage of being noninvasive and relatively cost-effective. However, a thorough NFPE has an unprecedented role in diagnosing malnutrition. SN - 2052-0034 UR - https://www.unboundmedicine.com/medline/citation/27174435/full_citation DB - PRIME DP - Unbound Medicine ER -