Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity.
Trends Neurosci. 2017 Jan; 40(1):1-3.TN

Abstract

Developmental brain plasticity involves complex, time-dependent dynamic molecular interactions that cannot be observed directly in humans. We propose that the shared evolutionary homology of teeth and the neurosensory system, and the archival nature of dentine microstructure, allows the development of 'biologic hard drives' that can characterize perinatal temporal dynamics in neuroplasticity.

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Authors+Show Affiliations

Morishita H

Department of Psychiatry, Neuroscience, and Ophthalmology, Friedman Brain Institute, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: hirofumi.morishita@mssm.edu.

Arora M

Division of Environmental Health, Department of Environmental Medicine and Public Health, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: manish.arora@mssm.edu.

MeSH

AnimalsBiological EvolutionBrainDental EnamelDentinHumansNeuronal PlasticityTooth

Pub Type(s)

Journal Article

Research Support, N.I.H., Extramural

Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

28038829

Citation

Morishita, Hirofumi, and Manish Arora. "Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity." Trends in Neurosciences, vol. 40, no. 1, 2017, pp. 1-3.

Morishita H, Arora M. Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity. Trends Neurosci. 2017;40(1):1-3.

Morishita, H., & Arora, M. (2017). Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity. Trends in Neurosciences, 40(1), 1-3. https://doi.org/10.1016/j.tins.2016.11.003

Morishita H, Arora M. Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity. Trends Neurosci. 2017;40(1):1-3. PubMed PMID: 28038829.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity. AU - Morishita,Hirofumi, AU - Arora,Manish, Y1 - 2016/12/27/ PY - 2016/09/01/received PY - 2016/11/18/accepted PY - 2017/1/1/entrez PY - 2017/1/1/pubmed PY - 2017/11/4/medline KW - biomarker KW - brain plasticity KW - critical period KW - teeth SP - 1 EP - 3 JF - Trends in neurosciences JO - Trends Neurosci VL - 40 IS - 1 N2 - Developmental brain plasticity involves complex, time-dependent dynamic molecular interactions that cannot be observed directly in humans. We propose that the shared evolutionary homology of teeth and the neurosensory system, and the archival nature of dentine microstructure, allows the development of 'biologic hard drives' that can characterize perinatal temporal dynamics in neuroplasticity. SN - 1878-108X UR - https://www.unboundmedicine.com/medline/citation/28038829/Tooth-Matrix_Biomarkers_to_Reconstruct_Critical_Periods_of_Brain_Plasticity. DB - PRIME DP - Unbound Medicine ER -

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Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity.Trends Neurosci. 2017 Jan; 40(1):1-3.TN