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Nutritional support in acute pancreatitis: from physiopathology to practice. An evidence-based approach.
Eur Rev Med Pharmacol Sci. 2017 01; 21(2):421-432.ER

Abstract

Acute Pancreatitis (AP) is a potentially fatal syndrome, associated with a hyper-catabolic state as well as early and late complications that may lead to multi-organ failure and death. Clinical researches produced in recent years suggest that acute pancreatitis may benefit from early oral or enteral nutrition. Nevertheless, many clinicians still believe erroneously that fasting - particularly in the early phase - may reduce AP complications and mortality. The goal of our review is to demonstrate that such false belief may harm the patients and that the whole management paradigm must change, adopting a more rational, evidence-based approach. First, we will describe AP physiopathology and the clinical assessment of its severity. Then we will discuss evidence-based data supporting early oral or enteral nutrition in AP. Finally, we will offer some practice recommendations as regards nutritional support.

Authors+Show Affiliations

Area Gastroenterologia, Nutrition Team, Fondazione Policlinico Universitario "A. Gemelli", Catholic University of the Sacred Heart, School of Medicine, Rome, Italy. emanurinni@yahoo.it.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28165542

Citation

Rinninella, E, et al. "Nutritional Support in Acute Pancreatitis: From Physiopathology to Practice. an Evidence-based Approach." European Review for Medical and Pharmacological Sciences, vol. 21, no. 2, 2017, pp. 421-432.
Rinninella E, Annetta MG, Serricchio ML, et al. Nutritional support in acute pancreatitis: from physiopathology to practice. An evidence-based approach. Eur Rev Med Pharmacol Sci. 2017;21(2):421-432.
Rinninella, E., Annetta, M. G., Serricchio, M. L., Dal Lago, A. A., Miggiano, G. A., & Mele, M. C. (2017). Nutritional support in acute pancreatitis: from physiopathology to practice. An evidence-based approach. European Review for Medical and Pharmacological Sciences, 21(2), 421-432.
Rinninella E, et al. Nutritional Support in Acute Pancreatitis: From Physiopathology to Practice. an Evidence-based Approach. Eur Rev Med Pharmacol Sci. 2017;21(2):421-432. PubMed PMID: 28165542.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutritional support in acute pancreatitis: from physiopathology to practice. An evidence-based approach. AU - Rinninella,E, AU - Annetta,M G, AU - Serricchio,M L, AU - Dal Lago,A A, AU - Miggiano,G A D, AU - Mele,M C, PY - 2017/2/7/entrez PY - 2017/2/7/pubmed PY - 2017/7/25/medline SP - 421 EP - 432 JF - European review for medical and pharmacological sciences JO - Eur Rev Med Pharmacol Sci VL - 21 IS - 2 N2 - Acute Pancreatitis (AP) is a potentially fatal syndrome, associated with a hyper-catabolic state as well as early and late complications that may lead to multi-organ failure and death. Clinical researches produced in recent years suggest that acute pancreatitis may benefit from early oral or enteral nutrition. Nevertheless, many clinicians still believe erroneously that fasting - particularly in the early phase - may reduce AP complications and mortality. The goal of our review is to demonstrate that such false belief may harm the patients and that the whole management paradigm must change, adopting a more rational, evidence-based approach. First, we will describe AP physiopathology and the clinical assessment of its severity. Then we will discuss evidence-based data supporting early oral or enteral nutrition in AP. Finally, we will offer some practice recommendations as regards nutritional support. SN - 2284-0729 UR - https://www.unboundmedicine.com/medline/citation/28165542/full_citation L2 - http://www.europeanreview.org/article/12113 DB - PRIME DP - Unbound Medicine ER -