Tags

Type your tag names separated by a space and hit enter

The influence of exercise on ulcer healing in patients with chronic venous insufficiency.
Int Angiol. 2018 Apr; 37(2):160-168.IA

Abstract

BACKGROUND

Venous leg ulcer (VLU) affects millions of people, and yet there have been no major advances in its treatment for many decades. Is it the time to change our approach, and try a multidisciplinary one that could bring about a change? The aim of this study is to evaluate whether a regular, home-based exercise could be influential in healing the VLU.

METHODS

Eighty subjects (mean age: 65.13 years) were recruited for 12 weeks. The participants were randomized into a control group (N.=20), a compression therapy group (N.=20), an exercise group (N.=20) and a compression and exercise group (N.=20). The exercise comprised of 10 dorsiflexions each hour while the patient was awake. The first 2 groups did not perform any exercise while the other two did. Baseline and 3-month measurements were performed. These measurements include skin perfusion assessment and ulcer size.

RESULTS

All patients showed low tcPO2 in the beginning of the study. At the point of 3 months of exercise, Laser Doppler flowmetry and ulcer size measurements showed significant decrease, P<0.001 in exercise groups, however, no real change was demonstrated in the non-exercise groups. Subjects who were performing exercise showed significant increase in tcPO2 readings after 3 months (P<0.001), whereas the tcPO2 readings remained the same in the non-exercise groups.

CONCLUSIONS

We concluded that exercise had a significant effect on the VLU healing and this effect may be enhanced further with the help of the compression therapy. The tcPO2 and RF measurements may be seen as useful tools in evaluating the microvascular changes, and monitoring healing and follow up of the venous leg ulcer.

Authors+Show Affiliations

Department of Surgery and Cancer, Imperial College London, London, UK - omar.mutlak07@imperial.ac.uk.Department of Surgery and Cancer, Imperial College London, London, UK.Department of Surgery and Cancer, Imperial College London, London, UK.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

29368880

Citation

Mutlak, Omar, et al. "The Influence of Exercise On Ulcer Healing in Patients With Chronic Venous Insufficiency." International Angiology : a Journal of the International Union of Angiology, vol. 37, no. 2, 2018, pp. 160-168.
Mutlak O, Aslam M, Standfield N. The influence of exercise on ulcer healing in patients with chronic venous insufficiency. Int Angiol. 2018;37(2):160-168.
Mutlak, O., Aslam, M., & Standfield, N. (2018). The influence of exercise on ulcer healing in patients with chronic venous insufficiency. International Angiology : a Journal of the International Union of Angiology, 37(2), 160-168. https://doi.org/10.23736/S0392-9590.18.03950-0
Mutlak O, Aslam M, Standfield N. The Influence of Exercise On Ulcer Healing in Patients With Chronic Venous Insufficiency. Int Angiol. 2018;37(2):160-168. PubMed PMID: 29368880.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The influence of exercise on ulcer healing in patients with chronic venous insufficiency. AU - Mutlak,Omar, AU - Aslam,Mohammed, AU - Standfield,Nigel, Y1 - 2018/01/25/ PY - 2018/1/26/pubmed PY - 2018/9/18/medline PY - 2018/1/26/entrez SP - 160 EP - 168 JF - International angiology : a journal of the International Union of Angiology JO - Int Angiol VL - 37 IS - 2 N2 - BACKGROUND: Venous leg ulcer (VLU) affects millions of people, and yet there have been no major advances in its treatment for many decades. Is it the time to change our approach, and try a multidisciplinary one that could bring about a change? The aim of this study is to evaluate whether a regular, home-based exercise could be influential in healing the VLU. METHODS: Eighty subjects (mean age: 65.13 years) were recruited for 12 weeks. The participants were randomized into a control group (N.=20), a compression therapy group (N.=20), an exercise group (N.=20) and a compression and exercise group (N.=20). The exercise comprised of 10 dorsiflexions each hour while the patient was awake. The first 2 groups did not perform any exercise while the other two did. Baseline and 3-month measurements were performed. These measurements include skin perfusion assessment and ulcer size. RESULTS: All patients showed low tcPO2 in the beginning of the study. At the point of 3 months of exercise, Laser Doppler flowmetry and ulcer size measurements showed significant decrease, P<0.001 in exercise groups, however, no real change was demonstrated in the non-exercise groups. Subjects who were performing exercise showed significant increase in tcPO2 readings after 3 months (P<0.001), whereas the tcPO2 readings remained the same in the non-exercise groups. CONCLUSIONS: We concluded that exercise had a significant effect on the VLU healing and this effect may be enhanced further with the help of the compression therapy. The tcPO2 and RF measurements may be seen as useful tools in evaluating the microvascular changes, and monitoring healing and follow up of the venous leg ulcer. SN - 1827-1839 UR - https://www.unboundmedicine.com/medline/citation/29368880/full_citation L2 - https://www.minervamedica.it/index2.t?show=R34Y2018N02A0160 DB - PRIME DP - Unbound Medicine ER -