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[Treatment of senile macular degeneration with Ginkgo biloba extract. A preliminary double-blind drug vs. placebo study].

Abstract

Senile macular degeneration is a frequent cause of blindness for which there is no satisfactory medical treatment. A double-blind trial comparing Ginkgo biloba extract with a placebo was conducted in 10 out-patients at the Hôpital Foch. Drug effectiveness was assessed on the results of fundoscopy and of measurements of visual acuity and visual field. In spite of the small population sample, a statistically significant improvement in long distance visual acuity was observed after treatment with Ginkgo biloba extract. The assumed pathogenesis of senile macular degeneration is discussed with emphasis on free oxygenated radicals.

Authors

, ,

Source

Presse medicale (Paris, France : 1983) 15:31 1986 Sep 25 pg 1556-8

MeSH

Aged
Clinical Trials as Topic
Double-Blind Method
Humans
Macular Degeneration
Middle Aged
Placebos
Plant Extracts
Plants, Medicinal
Time Factors
Trees
Visual Acuity

Pub Type(s)

Clinical Trial
Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial

Language

fre

PubMed ID

2947098

Citation

Lebuisson, D A., et al. "[Treatment of Senile Macular Degeneration With Ginkgo Biloba Extract. a Preliminary Double-blind Drug Vs. Placebo Study]." Presse Medicale (Paris, France : 1983), vol. 15, no. 31, 1986, pp. 1556-8.
Lebuisson DA, Leroy L, Rigal G. [Treatment of senile macular degeneration with Ginkgo biloba extract. A preliminary double-blind drug vs. placebo study]. Presse Med. 1986;15(31):1556-8.
Lebuisson, D. A., Leroy, L., & Rigal, G. (1986). [Treatment of senile macular degeneration with Ginkgo biloba extract. A preliminary double-blind drug vs. placebo study]. Presse Medicale (Paris, France : 1983), 15(31), pp. 1556-8.
Lebuisson DA, Leroy L, Rigal G. [Treatment of Senile Macular Degeneration With Ginkgo Biloba Extract. a Preliminary Double-blind Drug Vs. Placebo Study]. Presse Med. 1986 Sep 25;15(31):1556-8. PubMed PMID: 2947098.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Treatment of senile macular degeneration with Ginkgo biloba extract. A preliminary double-blind drug vs. placebo study]. AU - Lebuisson,D A, AU - Leroy,L, AU - Rigal,G, PY - 1986/9/25/pubmed PY - 1986/9/25/medline PY - 1986/9/25/entrez SP - 1556 EP - 8 JF - Presse medicale (Paris, France : 1983) JO - Presse Med VL - 15 IS - 31 N2 - Senile macular degeneration is a frequent cause of blindness for which there is no satisfactory medical treatment. A double-blind trial comparing Ginkgo biloba extract with a placebo was conducted in 10 out-patients at the Hôpital Foch. Drug effectiveness was assessed on the results of fundoscopy and of measurements of visual acuity and visual field. In spite of the small population sample, a statistically significant improvement in long distance visual acuity was observed after treatment with Ginkgo biloba extract. The assumed pathogenesis of senile macular degeneration is discussed with emphasis on free oxygenated radicals. SN - 0755-4982 UR - https://www.unboundmedicine.com/medline/citation/2947098/full_citation L2 - http://www.diseaseinfosearch.org/result/4401 DB - PRIME DP - Unbound Medicine ER -