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Healing of benign gastric ulcer with low-dose antacids and fiber diet.
Gastroenterology 1986; 91(1):56-61G

Abstract

A randomized, double-blind, placebo-controlled trial was conducted to determine the efficacy of a low-dose aluminum-magnesium antacid regimen (Link one tablet q.i.d.) (total neutralizing capacity 120 mmol HCl/day) in combination with a high- or a low-fiber diet in ulcer healing and relief of symptoms in patients with benign gastric ulcer. After 6 wk, the ulcer healed in 28 (67%) of the 42 patients treated with antacids compared with 11 (25%) of the 44 patients treated with placebo (p less than 0.001). Antacids were also significantly more effective than placebo in the relief of symptoms. The dietary treatment did not significantly influence ulcer healing or ulcer symptoms. Constipation was more frequently seen with the low- than with the high-fiber diet (p less than 0.01). No significant side effects from antacids were recorded.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

3011583

Citation

Rydning, A, et al. "Healing of Benign Gastric Ulcer With Low-dose Antacids and Fiber Diet." Gastroenterology, vol. 91, no. 1, 1986, pp. 56-61.
Rydning A, Weberg R, Lange O, et al. Healing of benign gastric ulcer with low-dose antacids and fiber diet. Gastroenterology. 1986;91(1):56-61.
Rydning, A., Weberg, R., Lange, O., & Berstad, A. (1986). Healing of benign gastric ulcer with low-dose antacids and fiber diet. Gastroenterology, 91(1), pp. 56-61.
Rydning A, et al. Healing of Benign Gastric Ulcer With Low-dose Antacids and Fiber Diet. Gastroenterology. 1986;91(1):56-61. PubMed PMID: 3011583.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Healing of benign gastric ulcer with low-dose antacids and fiber diet. AU - Rydning,A, AU - Weberg,R, AU - Lange,O, AU - Berstad,A, PY - 1986/7/1/pubmed PY - 1986/7/1/medline PY - 1986/7/1/entrez SP - 56 EP - 61 JF - Gastroenterology JO - Gastroenterology VL - 91 IS - 1 N2 - A randomized, double-blind, placebo-controlled trial was conducted to determine the efficacy of a low-dose aluminum-magnesium antacid regimen (Link one tablet q.i.d.) (total neutralizing capacity 120 mmol HCl/day) in combination with a high- or a low-fiber diet in ulcer healing and relief of symptoms in patients with benign gastric ulcer. After 6 wk, the ulcer healed in 28 (67%) of the 42 patients treated with antacids compared with 11 (25%) of the 44 patients treated with placebo (p less than 0.001). Antacids were also significantly more effective than placebo in the relief of symptoms. The dietary treatment did not significantly influence ulcer healing or ulcer symptoms. Constipation was more frequently seen with the low- than with the high-fiber diet (p less than 0.01). No significant side effects from antacids were recorded. SN - 0016-5085 UR - https://www.unboundmedicine.com/medline/citation/3011583/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/0016-5085(86)90438-5 DB - PRIME DP - Unbound Medicine ER -