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Association of Vegetarian Diet with Chronic Kidney Disease.
Nutrients. 2019 Jan 27; 11(2)N

Abstract

Chronic kidney disease (CKD) and its complications are major global public health issues. Vegetarian diets are associated with a more favorable profile of metabolic risk factors and lower blood pressure, but the protective effect in CKD is still unknown. We aim to assess the association between vegetarian diets and CKD. A cross-sectional study was based on subjects who received physical checkups at the Taipei Tzu Chi Hospital from 5 September 2005, to 31 December 2016. All subjects completed a questionnaire to assess their demographics, medical history, diet pattern, and lifestyles. The diet patterns were categorized into vegan, ovo-lacto vegetarian, or omnivore. CKD was defined as an estimated GFR <60 mL/min/1.73 m² or the presence of proteinuria. We evaluated the association between vegetarian diets and CKD prevalence by using multivariate analysis. Our study recruited 55,113 subjects. CKD was significantly less common in the vegan group compared with the omnivore group (vegan 14.8%, ovo-lacto vegetarians 20%, and omnivores 16.2%, P < 0.001). The multivariable logistic regression analysis revealed that vegetarian diets including vegan and ovo-lacto vegetarian diets were possible protective factors [odds ratios = 0.87 (0.77⁻0.99), P = 0.041; 0.84 (0.78⁻0.90), P < 0.001]. Our study showed a strong negative association between vegetarian diets and prevalence of CKD. If such associations are causal, vegetarian diets could be helpful in reducing the occurrence of CKD.

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Authors+Show Affiliations

Liu HW
Department of Family Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu-Chi Medical Foundation, New Taipei 231, Taiwan. kmichaelkkimo@gmail.com.
Tsai WH
Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, Taiwan. tsaiwh.tw@gmail.com. School of Medicine, Tzu Chi University, Hualien 970, Taiwan. tsaiwh.tw@gmail.com.
Liu JS
Division of Nephrology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, Taiwan. sgazn.tw@gmail.com.
Kuo KL
School of Medicine, Tzu Chi University, Hualien 970, Taiwan. kolinkuo8@gmail.com. Division of Nephrology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, Taiwan. kolinkuo8@gmail.com.

MeSH

AdultAgedCross-Sectional StudiesDiet, VegetarianHumansMiddle AgedRenal Insufficiency, ChronicRisk Factors

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30691237

Citation

Liu, Hao-Wen, et al. "Association of Vegetarian Diet With Chronic Kidney Disease." Nutrients, vol. 11, no. 2, 2019.
Liu HW, Tsai WH, Liu JS, et al. Association of Vegetarian Diet with Chronic Kidney Disease. Nutrients. 2019;11(2).
Liu, H. W., Tsai, W. H., Liu, J. S., & Kuo, K. L. (2019). Association of Vegetarian Diet with Chronic Kidney Disease. Nutrients, 11(2). https://doi.org/10.3390/nu11020279
Liu HW, et al. Association of Vegetarian Diet With Chronic Kidney Disease. Nutrients. 2019 Jan 27;11(2) PubMed PMID: 30691237.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of Vegetarian Diet with Chronic Kidney Disease. AU - Liu,Hao-Wen, AU - Tsai,Wen-Hsin, AU - Liu,Jia-Sin, AU - Kuo,Ko-Lin, Y1 - 2019/01/27/ PY - 2018/11/29/received PY - 2019/01/18/revised PY - 2019/01/24/accepted PY - 2019/1/30/entrez PY - 2019/1/30/pubmed PY - 2019/4/5/medline KW - chronic kidney disease KW - dietary pattern KW - vegetarian diet JF - Nutrients JO - Nutrients VL - 11 IS - 2 N2 - Chronic kidney disease (CKD) and its complications are major global public health issues. Vegetarian diets are associated with a more favorable profile of metabolic risk factors and lower blood pressure, but the protective effect in CKD is still unknown. We aim to assess the association between vegetarian diets and CKD. A cross-sectional study was based on subjects who received physical checkups at the Taipei Tzu Chi Hospital from 5 September 2005, to 31 December 2016. All subjects completed a questionnaire to assess their demographics, medical history, diet pattern, and lifestyles. The diet patterns were categorized into vegan, ovo-lacto vegetarian, or omnivore. CKD was defined as an estimated GFR <60 mL/min/1.73 m² or the presence of proteinuria. We evaluated the association between vegetarian diets and CKD prevalence by using multivariate analysis. Our study recruited 55,113 subjects. CKD was significantly less common in the vegan group compared with the omnivore group (vegan 14.8%, ovo-lacto vegetarians 20%, and omnivores 16.2%, P < 0.001). The multivariable logistic regression analysis revealed that vegetarian diets including vegan and ovo-lacto vegetarian diets were possible protective factors [odds ratios = 0.87 (0.77⁻0.99), P = 0.041; 0.84 (0.78⁻0.90), P < 0.001]. Our study showed a strong negative association between vegetarian diets and prevalence of CKD. If such associations are causal, vegetarian diets could be helpful in reducing the occurrence of CKD. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/30691237/full_citation DB - PRIME DP - Unbound Medicine ER -