Implications of the Westernized Diet in the Onset and Progression of IBD.
Nutrients. 2019 May 08; 11(5)N

Abstract

Inflammatory bowel diseases (IBD) are currently considered multifactorial pathologies in which various combined environmental factors act on a genetic background, giving rise to a chronic inflammation of the gastrointestinal tract. Among the various environmental factors, it now seems clear that the diet plays the major role in IBD onset and progression. Several clinical studies have attempted to understand the impact of diet in the development and progression of these diseases in order to establish useful guidelines for their management. However, the modest and sometimes contradictory results did not lead to the definition of shared dietary suggestions. On the other hand, food fads and recommendations based on anecdotal episodes are often followed by IBD patients to improve their diet. This review provides a critical overview of existing data on the role of diet as a risk factor for IBD. The methodology used was that of analyzing the results of clinical studies conducted on diet and IBD over the last 12 years through PubMed, as well as analyzing the most relevant studies on nutrients and their possible roles in IBD through the knowledge of the mechanisms by which they can modulate the microbiota or the intestinal physiology.

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Authors+Show Affiliations

Rizzello F

Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. fernando.rizzello@unibo.it.

Spisni E

Department of Biological, Geological and Environmental Sciences, University of Bologna, Via Selmi 3, 40126 Bologna, Italy. enzo.spisni@unibo.it.

Giovanardi E

Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. elisabett.giovanardi@studio.unibo.it.

Imbesi V

Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. veronica.imbesi@studio.unibo.it.

Salice M

Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. marco.salice@hotmail.com.

Alvisi P

Pediatric Unit, Maggiore Hospital, Largo Bartolo Nigrisoli, 2, 40133 Bologna, Italy. Patrizia.alvisi@ausl.bologna.it.

Valerii MC

Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. chiaravalerii@hotmail.it. Department of Biological, Geological and Environmental Sciences, University of Bologna, Via Selmi 3, 40126 Bologna, Italy. chiaravalerii@hotmail.it.

Gionchetti P

Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. paolo.gionchetti@unibo.it.

MeSH

Diet, WesternHumansInflammationInflammatory Bowel DiseasesRisk Factors

Pub Type(s)

Journal Article

Review

Language

eng

PubMed ID

31072001

Citation

Rizzello, Fernando, et al. "Implications of the Westernized Diet in the Onset and Progression of IBD." Nutrients, vol. 11, no. 5, 2019.

Rizzello F, Spisni E, Giovanardi E, et al. Implications of the Westernized Diet in the Onset and Progression of IBD. Nutrients. 2019;11(5).

Rizzello, F., Spisni, E., Giovanardi, E., Imbesi, V., Salice, M., Alvisi, P., Valerii, M. C., & Gionchetti, P. (2019). Implications of the Westernized Diet in the Onset and Progression of IBD. Nutrients, 11(5). https://doi.org/10.3390/nu11051033

Rizzello F, et al. Implications of the Westernized Diet in the Onset and Progression of IBD. Nutrients. 2019 May 8;11(5) PubMed PMID: 31072001.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Implications of the Westernized Diet in the Onset and Progression of IBD. AU - Rizzello,Fernando, AU - Spisni,Enzo, AU - Giovanardi,Elisabetta, AU - Imbesi,Veronica, AU - Salice,Marco, AU - Alvisi,Patrizia, AU - Valerii,Maria Chiara, AU - Gionchetti,Paolo, Y1 - 2019/05/08/ PY - 2019/04/07/received PY - 2019/05/02/revised PY - 2019/05/04/accepted PY - 2019/5/11/entrez PY - 2019/5/11/pubmed PY - 2020/1/7/medline KW - Inflammatory Bowel Disease (IBD) KW - Mediterranean Diet KW - Nutritional Approach KW - Western-style Diet (WSD) JF - Nutrients JO - Nutrients VL - 11 IS - 5 N2 - Inflammatory bowel diseases (IBD) are currently considered multifactorial pathologies in which various combined environmental factors act on a genetic background, giving rise to a chronic inflammation of the gastrointestinal tract. Among the various environmental factors, it now seems clear that the diet plays the major role in IBD onset and progression. Several clinical studies have attempted to understand the impact of diet in the development and progression of these diseases in order to establish useful guidelines for their management. However, the modest and sometimes contradictory results did not lead to the definition of shared dietary suggestions. On the other hand, food fads and recommendations based on anecdotal episodes are often followed by IBD patients to improve their diet. This review provides a critical overview of existing data on the role of diet as a risk factor for IBD. The methodology used was that of analyzing the results of clinical studies conducted on diet and IBD over the last 12 years through PubMed, as well as analyzing the most relevant studies on nutrients and their possible roles in IBD through the knowledge of the mechanisms by which they can modulate the microbiota or the intestinal physiology. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/31072001/full_citation DB - PRIME DP - Unbound Medicine ER -

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Implications of the Westernized Diet in the Onset and Progression of IBD.Nutrients. 2019 May 08; 11(5)N