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Protein redistribution diet restores motor function in patients with dopa-resistant "off" periods.
Neurology. 1988 Mar; 38(3):481-3.Neur

Abstract

Sixteen parkinsonians with acquired drug-resistant "off" periods without dyskinesia were placed on a diet in which virtually all protein was concentrated in the evening meal. Restoration of sensitivity to levodopa resulted in 88%. Ten patients (62%) have continued to comply with the diet for 7 months (mean). Two patients were studied in detail. Immobility correlated with elevated plasma levels of large neutral amino acids (LNAA), normality with low LNAA.

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Authors+Show Affiliations

Pincus JH
Yale University School of Medicine, Department of Neurology, New Haven, CT.
Barry K
No affiliation info available

MeSH

Amino AcidsDietary ProteinsDihydroxyphenylalanineDrug ResistanceFollow-Up StudiesHumansMotor ActivityOsmolar ConcentrationParkinson Disease

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3126411

Citation

Pincus, J H., and K Barry. "Protein Redistribution Diet Restores Motor Function in Patients With Dopa-resistant "off" Periods." Neurology, vol. 38, no. 3, 1988, pp. 481-3.
Pincus JH, Barry K. Protein redistribution diet restores motor function in patients with dopa-resistant "off" periods. Neurology. 1988;38(3):481-3.
Pincus, J. H., & Barry, K. (1988). Protein redistribution diet restores motor function in patients with dopa-resistant "off" periods. Neurology, 38(3), 481-3.
Pincus JH, Barry K. Protein Redistribution Diet Restores Motor Function in Patients With Dopa-resistant "off" Periods. Neurology. 1988;38(3):481-3. PubMed PMID: 3126411.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Protein redistribution diet restores motor function in patients with dopa-resistant "off" periods. AU - Pincus,J H, AU - Barry,K, PY - 1988/3/1/pubmed PY - 1988/3/1/medline PY - 1988/3/1/entrez SP - 481 EP - 3 JF - Neurology JO - Neurology VL - 38 IS - 3 N2 - Sixteen parkinsonians with acquired drug-resistant "off" periods without dyskinesia were placed on a diet in which virtually all protein was concentrated in the evening meal. Restoration of sensitivity to levodopa resulted in 88%. Ten patients (62%) have continued to comply with the diet for 7 months (mean). Two patients were studied in detail. Immobility correlated with elevated plasma levels of large neutral amino acids (LNAA), normality with low LNAA. SN - 0028-3878 UR - https://www.unboundmedicine.com/medline/citation/3126411/full_citation L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=3126411.ui DB - PRIME DP - Unbound Medicine ER -