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Protein redistribution diet restores motor function in patients with dopa-resistant "off" periods.
Sixteen parkinsonians with acquired drug-resistant "off" periods without dyskinesia were placed on a diet in which virtually all protein was concentrated in the evening meal. Restoration of sensitivity to levodopa resulted in 88%. Ten patients (62%) have continued to comply with the diet for 7 months (mean). Two patients were studied in detail. Immobility correlated with elevated plasma levels of large neutral amino acids (LNAA), normality with low LNAA.
Yale University School of Medicine, Department of Neurology, New Haven, CT.
Pub Type(s)Journal Article
Research Support, Non-U.S. Gov't