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Potential interventions for novel coronavirus in China: A systematic review.
J Med Virol. 2020 05; 92(5):479-490.JM

Abstract

An outbreak of a novel coronavirus (COVID-19 or 2019-CoV) infection has posed significant threats to international health and the economy. In the absence of treatment for this virus, there is an urgent need to find alternative methods to control the spread of disease. Here, we have conducted an online search for all treatment options related to coronavirus infections as well as some RNA-virus infection and we have found that general treatments, coronavirus-specific treatments, and antiviral treatments should be useful in fighting COVID-19. We suggest that the nutritional status of each infected patient should be evaluated before the administration of general treatments and the current children's RNA-virus vaccines including influenza vaccine should be immunized for uninfected people and health care workers. In addition, convalescent plasma should be given to COVID-19 patients if it is available. In conclusion, we suggest that all the potential interventions be implemented to control the emerging COVID-19 if the infection is uncontrollable.

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    Authors+Show Affiliations

    Zhang L
    Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
    Liu Y
    Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.

    MeSH

    Antiviral AgentsBetacoronavirusChinaCoronavirus InfectionsHumansImmunization, PassiveImmunologic FactorsNutritional StatusPlasmaPneumonia, ViralTrace ElementsViral VaccinesVitamins

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    32052466

    Citation

    Zhang, Lei, and Yunhui Liu. "Potential Interventions for Novel Coronavirus in China: a Systematic Review." Journal of Medical Virology, vol. 92, no. 5, 2020, pp. 479-490.
    Zhang L, Liu Y. Potential interventions for novel coronavirus in China: A systematic review. J Med Virol. 2020;92(5):479-490.
    Zhang, L., & Liu, Y. (2020). Potential interventions for novel coronavirus in China: A systematic review. Journal of Medical Virology, 92(5), 479-490. https://doi.org/10.1002/jmv.25707
    Zhang L, Liu Y. Potential Interventions for Novel Coronavirus in China: a Systematic Review. J Med Virol. 2020;92(5):479-490. PubMed PMID: 32052466.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Potential interventions for novel coronavirus in China: A systematic review. AU - Zhang,Lei, AU - Liu,Yunhui, Y1 - 2020/03/03/ PY - 2020/01/30/received PY - 2020/02/04/accepted PY - 2020/2/14/pubmed PY - 2020/3/19/medline PY - 2020/2/14/entrez KW - 2019-CoV KW - COVID-19 KW - MERS KW - SARS KW - coronavirus KW - potential interventions SP - 479 EP - 490 JF - Journal of medical virology JO - J. Med. Virol. VL - 92 IS - 5 N2 - An outbreak of a novel coronavirus (COVID-19 or 2019-CoV) infection has posed significant threats to international health and the economy. In the absence of treatment for this virus, there is an urgent need to find alternative methods to control the spread of disease. Here, we have conducted an online search for all treatment options related to coronavirus infections as well as some RNA-virus infection and we have found that general treatments, coronavirus-specific treatments, and antiviral treatments should be useful in fighting COVID-19. We suggest that the nutritional status of each infected patient should be evaluated before the administration of general treatments and the current children's RNA-virus vaccines including influenza vaccine should be immunized for uninfected people and health care workers. In addition, convalescent plasma should be given to COVID-19 patients if it is available. In conclusion, we suggest that all the potential interventions be implemented to control the emerging COVID-19 if the infection is uncontrollable. SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/32052466/full_citation L2 - https://doi.org/10.1002/jmv.25707 DB - PRIME DP - Unbound Medicine ER -