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Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications.
Int J Nanomedicine. 2020; 15:3099-3120.IJ

Abstract

Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic application of curcumin is limited by its extremely low solubility in aqueous buffer, instability in body fluids, and rapid metabolism. Nano delivery system has shown excellent potential to improve the solubility, biocompatibility and therapeutic effect of curcumin. In this review, we focus on the recent development of nano encapsulated curcumin and its potential for biomedical applications.

Authors+Show Affiliations

School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.Division of Pharmaceutics and Pharmacology, The Ohio State University, Columbus, OH, USA.School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32431504

Citation

Chen, Yan, et al. "Nano Encapsulated Curcumin: and Its Potential for Biomedical Applications." International Journal of Nanomedicine, vol. 15, 2020, pp. 3099-3120.
Chen Y, Lu Y, Lee RJ, et al. Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications. Int J Nanomedicine. 2020;15:3099-3120.
Chen, Y., Lu, Y., Lee, R. J., & Xiang, G. (2020). Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications. International Journal of Nanomedicine, 15, 3099-3120. https://doi.org/10.2147/IJN.S210320
Chen Y, et al. Nano Encapsulated Curcumin: and Its Potential for Biomedical Applications. Int J Nanomedicine. 2020;15:3099-3120. PubMed PMID: 32431504.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications. AU - Chen,Yan, AU - Lu,Yao, AU - Lee,Robert J, AU - Xiang,Guangya, Y1 - 2020/05/01/ PY - 2020/01/30/received PY - 2020/04/07/accepted PY - 2020/5/21/entrez PY - 2020/5/21/pubmed PY - 2020/8/1/medline KW - bioavailability KW - curcumin KW - nanoformulations KW - nanoparticles KW - therapy SP - 3099 EP - 3120 JF - International journal of nanomedicine JO - Int J Nanomedicine VL - 15 N2 - Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic application of curcumin is limited by its extremely low solubility in aqueous buffer, instability in body fluids, and rapid metabolism. Nano delivery system has shown excellent potential to improve the solubility, biocompatibility and therapeutic effect of curcumin. In this review, we focus on the recent development of nano encapsulated curcumin and its potential for biomedical applications. SN - 1178-2013 UR - https://www.unboundmedicine.com/medline/citation/32431504/Nano_Encapsulated_Curcumin:_And_Its_Potential_for_Biomedical_Applications_ DB - PRIME DP - Unbound Medicine ER -