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Oxygen radicals and human disease.
Ann Intern Med 1987; 107(4):526-45AIM

Abstract

Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron and of various antioxidants as well as the diseases that have received active attention in oxy-radical research. Particular attention is focused on cigarette smoke oxidants, ischemia-reperfusion-induced radical production, carcinogenesis, and aging. Such research may well provide a firm foundation for therapeutic breakthroughs.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

3307585

Citation

Cross, C E., et al. "Oxygen Radicals and Human Disease." Annals of Internal Medicine, vol. 107, no. 4, 1987, pp. 526-45.
Cross CE, Halliwell B, Borish ET, et al. Oxygen radicals and human disease. Ann Intern Med. 1987;107(4):526-45.
Cross, C. E., Halliwell, B., Borish, E. T., Pryor, W. A., Ames, B. N., Saul, R. L., ... Harman, D. (1987). Oxygen radicals and human disease. Annals of Internal Medicine, 107(4), pp. 526-45.
Cross CE, et al. Oxygen Radicals and Human Disease. Ann Intern Med. 1987;107(4):526-45. PubMed PMID: 3307585.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oxygen radicals and human disease. AU - Cross,C E, AU - Halliwell,B, AU - Borish,E T, AU - Pryor,W A, AU - Ames,B N, AU - Saul,R L, AU - McCord,J M, AU - Harman,D, PY - 1987/10/1/pubmed PY - 1987/10/1/medline PY - 1987/10/1/entrez SP - 526 EP - 45 JF - Annals of internal medicine JO - Ann. Intern. Med. VL - 107 IS - 4 N2 - Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron and of various antioxidants as well as the diseases that have received active attention in oxy-radical research. Particular attention is focused on cigarette smoke oxidants, ischemia-reperfusion-induced radical production, carcinogenesis, and aging. Such research may well provide a firm foundation for therapeutic breakthroughs. SN - 0003-4819 UR - https://www.unboundmedicine.com/medline/citation/3307585/full_citation L2 - https://www.annals.org/article.aspx?volume=107&issue=4&page=526 DB - PRIME DP - Unbound Medicine ER -