Approach to Fatigue: Best Practice.
Med Clin North Am. 2021 Jan; 105(1):137-148.MC

Abstract

Owing to the broad differential diagnoses that can present as fatigue, a rational approach to diagnosis is paramount. Performance of a battery of diagnostic tests is unlikely to assist with diagnosis, highlighting the importance of a thorough history and physical examination. Fatigue can be a sequela of an underlying medical disease or exists as a primary condition. Management of secondary fatigue largely depends on treatment of the underlying condition. There are no FDA-approved medications for primary fatigue, now known as system exertion intolerance disease. Treatment is focused on individualized exercise therapy and cognitive behavioral therapy.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Dukes JC

Internal Medicine Department, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 565, Norfolk, VA 23507, USA. Electronic address: dukesjc@evms.edu.

Chakan M

Internal Medicine Department, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 481, Norfolk, VA 23507, USA.

Mills A

Internal Medicine Department, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 483, Norfolk, VA 23507, USA.

Marcaurd M

Internal Medicine Department, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 572, Norfolk, VA 23507, USA.

MeSH

Cognitive Behavioral TherapyDepressionDiagnosis, DifferentialEvidence-Based MedicineExercise TherapyFatigueFatigue Syndrome, ChronicHumansHypothyroidismMedical History TakingPrimary Health Care

Pub Type(s)

Journal Article

Review

Language

eng

PubMed ID

33246515

Citation

Dukes, Jason C., et al. "Approach to Fatigue: Best Practice." The Medical Clinics of North America, vol. 105, no. 1, 2021, pp. 137-148.

Dukes JC, Chakan M, Mills A, et al. Approach to Fatigue: Best Practice. Med Clin North Am. 2021;105(1):137-148.

Dukes, J. C., Chakan, M., Mills, A., & Marcaurd, M. (2021). Approach to Fatigue: Best Practice. The Medical Clinics of North America, 105(1), 137-148. https://doi.org/10.1016/j.mcna.2020.09.007

Dukes JC, et al. Approach to Fatigue: Best Practice. Med Clin North Am. 2021;105(1):137-148. PubMed PMID: 33246515.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Approach to Fatigue: Best Practice. AU - Dukes,Jason C, AU - Chakan,Matthew, AU - Mills,Aaron, AU - Marcaurd,Maurice, PY - 2020/11/28/entrez PY - 2020/11/29/pubmed PY - 2020/12/15/medline KW - Chronic fatigue syndrome KW - Fatigue KW - Myalgic encephalitis KW - Sleepiness KW - Systemic exertion intolerance disease KW - Tiredness SP - 137 EP - 148 JF - The Medical clinics of North America JO - Med Clin North Am VL - 105 IS - 1 N2 - Owing to the broad differential diagnoses that can present as fatigue, a rational approach to diagnosis is paramount. Performance of a battery of diagnostic tests is unlikely to assist with diagnosis, highlighting the importance of a thorough history and physical examination. Fatigue can be a sequela of an underlying medical disease or exists as a primary condition. Management of secondary fatigue largely depends on treatment of the underlying condition. There are no FDA-approved medications for primary fatigue, now known as system exertion intolerance disease. Treatment is focused on individualized exercise therapy and cognitive behavioral therapy. SN - 1557-9859 UR - https://www.unboundmedicine.com/medline/citation/33246515/Approach_to_Fatigue:_Best_Practice_ DB - PRIME DP - Unbound Medicine ER -

Tags

Approach to Fatigue: Best Practice.Med Clin North Am. 2021 Jan; 105(1):137-148.MC