Segregation analysis of migraine in 128 families.Cephalalgia. 1986 Jun; 6(2):101-5.C
Abstract
To test the existence of inherited liability to migraine, formal segregation analysis of family data collected from 128 patients has been performed. Patients were subdivided into three groups in accordance with the presence or absence of migraine in their parents. The results obtained in each group were then compared with those expected on the basis of two different modes of simple Mendelian inheritance, namely autosomal dominant and autosomal recessive transmission. Our data show that neither of the two hypotheses can be accepted, thus suggesting the existence of a possible genetic heterogeneity of liability to migraine.
MeSH
Pub Type(s)
Journal Article
Language
eng
PubMed ID
3527442
Citation
Devoto, M, et al. "Segregation Analysis of Migraine in 128 Families." Cephalalgia : an International Journal of Headache, vol. 6, no. 2, 1986, pp. 101-5.
Devoto M, Lozito A, Staffa G, et al. Segregation analysis of migraine in 128 families. Cephalalgia. 1986;6(2):101-5.
Devoto, M., Lozito, A., Staffa, G., D'Alessandro, R., Sacquegna, T., & Romeo, G. (1986). Segregation analysis of migraine in 128 families. Cephalalgia : an International Journal of Headache, 6(2), 101-5.
Devoto M, et al. Segregation Analysis of Migraine in 128 Families. Cephalalgia. 1986;6(2):101-5. PubMed PMID: 3527442.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Segregation analysis of migraine in 128 families.
AU - Devoto,M,
AU - Lozito,A,
AU - Staffa,G,
AU - D'Alessandro,R,
AU - Sacquegna,T,
AU - Romeo,G,
PY - 1986/6/1/pubmed
PY - 1986/6/1/medline
PY - 1986/6/1/entrez
SP - 101
EP - 5
JF - Cephalalgia : an international journal of headache
JO - Cephalalgia
VL - 6
IS - 2
N2 - To test the existence of inherited liability to migraine, formal segregation analysis of family data collected from 128 patients has been performed. Patients were subdivided into three groups in accordance with the presence or absence of migraine in their parents. The results obtained in each group were then compared with those expected on the basis of two different modes of simple Mendelian inheritance, namely autosomal dominant and autosomal recessive transmission. Our data show that neither of the two hypotheses can be accepted, thus suggesting the existence of a possible genetic heterogeneity of liability to migraine.
SN - 0333-1024
UR - https://www.unboundmedicine.com/medline/citation/3527442/full_citation
DB - PRIME
DP - Unbound Medicine
ER -
