The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health.
Microorganisms. 2023 Aug 22; 11(9)M

Abstract

The emergence of antimicrobial resistance (AMR) is a global health problem without geographic boundaries. This increases the risk of complications and, thus, makes it harder to treat infections, which can result in higher healthcare costs and a greater number of deaths. Antimicrobials are often used to treat infections from pathogens in food-producing animals, making them a potential source of AMR. Overuse and misuse of these drugs in animal agriculture can lead to the development of AMR bacteria, which can then be transmitted to humans through contaminated food or direct contact. It is therefore essential to take multifaceted, comprehensive, and integrated measures, following the One Health approach. To address this issue, many countries have implemented regulations to limit antimicrobial use. To our knowledge, there are previous studies based on AMR in food-producing animals; however, this paper adds novelty related to the AMR pathogens in livestock, as we include the recent publications of this field worldwide. In this work, we aim to describe the most critical and high-risk AMR pathogens among food-producing animals, as a worldwide health problem. We also focus on the dissemination of AMR genes in livestock, as well as its consequences in animals and humans, and future strategies to tackle this threat.

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Authors+Show Affiliations

Almansour AM

Molecular Biology Division, Reference Laboratory for Microbiology, Executive Department of Reference Laboratories, Research and Laboratories Sector, Saudi Food and Drug Authority (SFDA), Riyadh 11671, Saudi Arabia.

Alhadlaq MA

Alzahrani KO

Mukhtar LE

Antimicrobial Resistance Division, Reference Laboratory for Microbiology, Executive Department of Reference Laboratories, Research and Laboratories Sector, Saudi Food and Drug Authority (SFDA), Riyadh 11671, Saudi Arabia.

Alharbi AL

Alajel SM

Reference Laboratory for Microbiology, Executive Department of Reference Laboratories, Research and Laboratories Sector, Saudi Food and Drug Authority (SFDA), Riyadh 11671, Saudi Arabia.

Pub Type(s)

Journal Article

Review

Language

eng

PubMed ID

37763971

Citation

Almansour, Ayidh M., et al. "The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact On Public Health." Microorganisms, vol. 11, no. 9, 2023.

Almansour AM, Alhadlaq MA, Alzahrani KO, et al. The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health. Microorganisms. 2023;11(9).

Almansour, A. M., Alhadlaq, M. A., Alzahrani, K. O., Mukhtar, L. E., Alharbi, A. L., & Alajel, S. M. (2023). The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health. Microorganisms, 11(9). https://doi.org/10.3390/microorganisms11092127

Almansour AM, et al. The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact On Public Health. Microorganisms. 2023 Aug 22;11(9) PubMed PMID: 37763971.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health. AU - Almansour,Ayidh M, AU - Alhadlaq,Meshari A, AU - Alzahrani,Khaloud O, AU - Mukhtar,Lenah E, AU - Alharbi,Abdulmohsen L, AU - Alajel,Sulaiman M, Y1 - 2023/08/22/ PY - 2023/7/9/received PY - 2023/8/10/revised PY - 2023/8/16/accepted PY - 2023/9/28/medline PY - 2023/9/28/pubmed PY - 2023/9/28/entrez KW - One Health approach KW - antibiotics KW - foodborne KW - healthcare costs KW - livestock KW - multidrug resistance KW - pathogens JF - Microorganisms JO - Microorganisms VL - 11 IS - 9 N2 - The emergence of antimicrobial resistance (AMR) is a global health problem without geographic boundaries. This increases the risk of complications and, thus, makes it harder to treat infections, which can result in higher healthcare costs and a greater number of deaths. Antimicrobials are often used to treat infections from pathogens in food-producing animals, making them a potential source of AMR. Overuse and misuse of these drugs in animal agriculture can lead to the development of AMR bacteria, which can then be transmitted to humans through contaminated food or direct contact. It is therefore essential to take multifaceted, comprehensive, and integrated measures, following the One Health approach. To address this issue, many countries have implemented regulations to limit antimicrobial use. To our knowledge, there are previous studies based on AMR in food-producing animals; however, this paper adds novelty related to the AMR pathogens in livestock, as we include the recent publications of this field worldwide. In this work, we aim to describe the most critical and high-risk AMR pathogens among food-producing animals, as a worldwide health problem. We also focus on the dissemination of AMR genes in livestock, as well as its consequences in animals and humans, and future strategies to tackle this threat. SN - 2076-2607 UR - https://www.unboundmedicine.com/medline/citation/37763971/full_citation DB - PRIME DP - Unbound Medicine ER -

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The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health.Microorganisms. 2023 Aug 22; 11(9)M